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Ligand 6-methylthio-2-oxohexanoate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.3.17

6-methylthio-2-oxohexanoate + acetyl-CoA + H2O = 2-(4-methylthiobutyl)malate + CoA

741321, 741153, 741197, 741119

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

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Show Turnover Number (1 entry)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

2.3.3.17

2.5

-

at pH 8.0 and 32°C

741197

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.3.3.17

0.463

-

at pH 8.0 and 32°C

741197

References & Links

Literature References (4)

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Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

741119

-

Methylthioalkylmalate synthases: Genetics, ecology and evolution

2009

Benderoth, M.; Pfalz, M.; Kroymann, J.

Phytochem. Rev.

8

255-268

741153

21205930

From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis

2011

de Kraker, J.W.; Gershenzon, J.

Plant Cell

23

38-53

741197

17369439

MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis

2007

Textor, S.; de Kraker, J.W.; Hause, B.; Gershenzon, J.; Tokuhisa, J.G.

Plant Physiol.

144

60-71

741321

16754868

Positive selection driving diversification in plant secondary metabolism

2006

Benderoth, M.; Textor, S.; Windsor, A.; Mitchell-Olds, T.; Gershenzon, J.; Kroymann, J.

Proc. Natl. Acad. Sci. USA

103

9118-9123

Links to other databases for 6-methylthio-2-oxohexanoate

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Show Links (1 entry)

ChEBI

PubChem