Ligand 2-phenylpropionic acid
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Basic Ligand Information
Molecular Structure

C9H10O2
2-phenylpropionic acid
YPGCWEMNNLXISK-UHFFFAOYSA-N
2-arylpropionate, 2-phenylpropanoate, 2-phenylpropanoic acid, 2-phenylpropionate, alpha-methylphenylacetic acid, alpha-phenylpropionate
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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2-aryl-2-methylmalonate + H+ = 2-arylpropionate + CO2
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2-aryl-2-methylmalonate = 2-arylpropionate + CO2
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Substrate in Enzyme-catalyzed Reactions (3 results)
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2-phenylpropionic acid + ? = ?
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2-phenylpropanoate = ethylbenzene + CO2
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ATP + 2-phenylpropanoic acid + CoA = AMP + diphosphate + 2-phenylpropanoyl-CoA
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Product in Enzyme-catalyzed Reactions (14 results)
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alpha-phenylpropanal + NAD+ + H2O = alpha-phenylpropionate + NADH
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4-nitrophenyl 2-phenylpropanoate + H2O = 4-nitrophenol + 2-phenylpropanoate
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2 2-phenylpropionitrile + 3 H2O = 2-phenylpropanoic acid + 2-phenylpropanamide + NH3
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2-phenylpropionitrile + 2 H2O = 2-phenylpropionic acid + NH3
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2-phenylpropionitrile + H2O = 2-phenylpropionate + NH3
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(R,S)-2-phenylpropionitrile + 2 H2O = 2-phenylpropionic acid + NH3
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2 (R,S)-2-phenylpropionitrile + 3 H2O = 2-phenylpropionic acid + 2-phenylpropionamide + NH3
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2-phenylpropionitrile + 2 H2O = 2-phenylpropionic acid + NH3
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alpha-methylphenylacetonitrile + H2O = alpha-methylphenylacetic acid + NH3
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2-phenylbutyronitrile + 2 H2O = 2-phenylpropionic acid + NH3
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2-phenylpropionitrile + 2 H2O = 2-phenylpropionic acid + NH3
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2-aryl-2-methylmalonate + H+ = 2-arylpropionate + CO2
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2-aryl-2-methylmalonate = 2-arylpropionate + CO2
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2-methyl-2-phenylmalonate = 2-phenylpropanoate + CO2
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Enzyme Kinetic Parameters
References & Links
Literature References (4)
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Purification and characterization of the 4-hydroxyphenylacetic acid-3-hydroxylase from Pseudomonas putida U
1997
Fernandez-Medarde, A.; Luengo, J.M.
FEMS Microbiol. Lett.
157
47-53
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Characterization and partial purification of an enantioselective arylacetonitrilase from Pseudomonas fluorescens DSM 7155
1998
Layh, N.; Parratt, J.; Willetts, A.
J. Mol. Catal. B
5
467-474
New application of firefly luciferase - it can catalyze the enantioselective thioester formation of 2-arylpropanoic acid
2007
Kato, D.; Teruya, K.; Yoshida, H.; Takeo, M.; Negoro, S.; Ohta, H.
FEBS J.
274
3877-3885
In vitro characterization of phenylacetate decarboxylase, a novel enzyme catalyzing toluene biosynthesis in an anaerobic microbial community
2016
Zargar, K.; Saville, R.; Phelan, R.M.; Tringe, S.G.; Petzold, C.J.; Keasling, J.D.; Beller, H.R.
Sci. Rep.
6
31362
Links to other databases for 2-phenylpropionic acid