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Ligand tryprostatin B
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Basic Ligand Information
BRENDA
MetaCyc
Show all BRENDA pathways known for tryprostatin B
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open all tablesRoles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 = 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)
EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Substrate in Enzyme-catalyzed Reactions (2 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 = 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O
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tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 = demethoxyfumitremorgin C + [oxidized NADPH-hemoprotein reductase] + H2O
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Product in Enzyme-catalyzed Reactions (5 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylallyl diphosphate + cyclo-(D-Trp-L-Pro) = diphosphate + cyclo-(2-dimethylallyl-Trp-L-Pro)
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dimethylallyl diphosphate + cyclo-(L-Trp-L-Pro) = diphosphate + cyclo-(2-dimethylallyl-Trp-L-Pro)
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dimethylallyl diphosphate + brevianamide F = diphosphate + (5aS,6aR,11aS,13aS)-6a-(2-methylbut-3-en-2-yl)-2,3,6,6a,11,11a-hexahydro-1H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(5aH,13aH)-dione + tryprostatin B
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
Links to other databases for tryprostatin B
ChEBI
PubChem
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Release 2023.1 (January 2023)
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