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Ligand 4-fluorobenzonitrile

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

LITERATURE

REACTION DIAGRAM

PROVEN IN VIVO REACTION

ENZYME 3D STRUCTURE

3.5.5.1

719103

4-fluorobenzonitrile + 2 H2O = 4-fluorobenzoic acid + NH3

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Substrate in Enzyme-catalyzed Reactions (5 results)

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Show Substrate (5 entries)

EC NUMBER

LITERATURE

REACTION DIAGRAM

REACTION

ENZYME 3D STRUCTURE

1.14.12.26

746689

4-fluorobenzonitrile + NADH + H+ + O2 = cis-1,2-dihydroxy-3-cyanocyclohexa-6-fluoro-3,5-diene + NAD+

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3.5.5.1

719103

4-fluorobenzonitrile + 2 H2O = 4-fluorobenzoic acid + NH3

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3.5.5.1

209762, 209761, 209746

4-fluorobenzonitrile + H2O = 4-fluorobenzoic acid + NH3

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4.2.1.84

706803

4-fluorobenzonitrile + H2O = 4-fluorbenzamide

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4.2.1.84

706803

4-fluorobenzonitrile + H2O = 4-fluorobenzamide

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3.5.5.1

2 entries

4.2.1.84

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

209746

10591020

Characterization of an inducible nitrilase from a thermophilic bacillus

1999

Almatawah, Q.A.; Cramp, R.; Cowan, D.A.

Extremophiles

3

283-291

209761

23761

Fungal degradation of aromatic nitriles. Enzymology of C-N cleavage by Fusarium solani

1977

Harper, D.B.

Biochem. J.

167

685-692

209762

21655

Microbial metabolism of aromatic nitriles. Enzymology of C-N cleavage by Nocardia sp. (Rhodococcus group) N.C.I.B. 11216

1977

Harper, D.B.

Biochem. J.

165

309-319

706803

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Biotransformation of nitriles using the solvent-tolerant nitrile hydratase from Rhodopseudomonas palustris CGA009

2010

Black, G.; Gregson, T.; McPake, C.; Perry, J.; Zhang, M.

Tetrahedron Lett.

51

1639-1641

719103

21188422

Optimization of nitrilase production from Alcaligenes faecalis MTCC 10757 (IICT-A3): effect of inducers on substrate specificity

2011

Nageshwar, Y.V.; Sheelu, G.; Shambhu, R.R.; Muluka, H.; Mehdi, N.; Malik, M.S.; Kamal, A.

Bioprocess Biosyst. Eng.

34

515-523

746689

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Recombinant chlorobenzene dioxygenase from Pseudomonas sp. P51 A biocatalyst for regioselective oxidation of aromatic nitriles

2005

Yildirim, S.; Franko, T.; Wohlgemuth, R.; Kohler, H.; Witholt, B.; Schmid, A.

Adv. Synth. Catal.

347

1060-1072

Links to other databases for 4-fluorobenzonitrile

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Show Links (1 entry)

ChEBI

PubChem

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