Ligand nitrobenzoxadiazole-labeled sphingosine

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Basic Ligand Information

Molecular Structure
Picture of nitrobenzoxadiazole-labeled sphingosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H49N5O6
nitrobenzoxadiazole-labeled sphingosine
HZIRBXILQRLFIK-VPZZKNKNSA-N
Synonyms:
(6-[N-(7-nitrobenz-2-oxa-1,3 diazol-4-yl)amino]hexanoyl)sphingosine, 4-nitrobenzo-2-oxa-1,3-diazole-N-hexanoylsphingosine, 6-(((N-7-nitrobenz-2-oxa-1,3-diazol-4yl)amino)caproyl)sphingosine, 6-[N-(7-nitrobenz-2-oxa-1,3 diazol-4-yl)amino]hexanoyl)ceramide, C6-7-nitro-2,1,3-benzoxadiazole-ceramide, C6-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)ceramide, N-(6-((7-nitro-2-1,3-benzoxadiazol-4-yl)amino)hexanoyl)-D-erythro-sphingosine, N-(6-((7-nitrobenz-2-oxa-1.3-diazol-4-yl)amino)hexanoyl)-sphingosine, N-(6-[(7-nitro-benz-2-oxa-1,3-diazo-4-yl)amino]caproyl)-ceramide, N-6-[(7-nitrobenzo-2-oxa-1,3-diazol-4-yl)amino]hexanoyl-4-D-erythro-sphingosine, N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine, N-[7-(4-nitrobenzo-2-oxa-1,3-diazole)]-6-aminocaproyl-D-erythro-sphingosine, N-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}sphingosine, NBD-C6-ceramide, NBD C6-ceramide

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-(6-((7-nitro-2-1,3-benzoxadiazol-4-yl)amino)hexanoyl)-D-erythro-sphingosine + ATP = N-(6-((7-nitro-2-1,3-benzoxadiazol-4-yl)amino)hexanoyl)-D-erythro-sphingosine 1-phosphate + ADP
show the reaction diagram
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ATP + N-[7-(4-nitrobenzo-2-oxa-1,3-diazole)]-6-aminocaproyl-D-erythro-sphingosine = ADP + N-[7-(4-nitrobenzo-2-oxa-1,3-diazole)]-6-aminocaproyl-D-erythro-sphingosine 1-phosphate
show the reaction diagram
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4-nitrobenzo-2-oxa-1,3-diazole-N-hexanoylsphingosine + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-[[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-hexanoyl]-sphingosine-1-phosphocholine + H2O = N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine + phosphorylcholine
show the reaction diagram
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C6-7-nitro-2,1,3-benzoxadiazole-GlcCer = C6-7-nitro-2,1,3-benzoxadiazole-ceramide + beta-D-glucose
show the reaction diagram
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Enzyme Kinetic Parameters

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.03877
-
substrate is fluorescent
0.001
-
-

References & Links

Links to other databases for nitrobenzoxadiazole-labeled sphingosine

ChEBI
PubChem
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PubChem