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Ligand 2-chloroacrylic acid Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C3 H3 ClO2
2-chloroacrylic acid
SZTBMYHIYNGYIA-UHFFFAOYSA-N
2-chloroacrylate, chloroacrylic acid
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-chloroacrylate + NADPH + H+ = (S)-2-chloropropanoate + NADP+
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Substrate in Enzyme-catalyzed Reactions (3 results)
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2-chloroacrylate + NADPH + H+ = (S)-2-chloropropanoate + NADP+
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chloroacrylic acid + NADPH = (S)-2-chloropropionic acid + NADP+
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2-chloroacrylate + H2O = 2-hydroxyacrylate + HCl
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Product in Enzyme-catalyzed Reactions (1 result)
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2-chloroacrylonitrile + H2O = 2-chloroacrylic acid + NH3
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links Literature References (5)
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Purification and characterization of thermostable and nonthermostable 2-haloacid dehalogenases with different stereospecificities from Pseudomonas sp. strain YL
1994
Liu, J.Q.; Kurihara, T.; Hasan, A.K.M.Q.; Nardi-Dei, V.; Koshikawa, H.; Esaki, N.; Soda, K.
Appl. Environ. Microbiol.
60
2389-2393
Asymmetric bioreduction of activated C:C bonds using enoate reductases from the old yellow enzyme family
2007
Stuermer, R.; Hauer, B.; Hall, M.; Faber, K.
Curr. Opin. Chem. Biol.
11
203-213
A mechanistic analysis of enzymatic degradation of organohalogen compounds
2011
Kurihara, T.
Biosci. Biotechnol. Biochem.
75
189-198
2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds
2005
Kurata, A.; Kurihara, T.; Kamachi, H.; Esaki N.
J. Biol. Chem.
280
20286-20291
Production of (S)-2-chloropropionate by asymmetric reduction of 2-chloroacrylate with 2-haloacrylate reductase coupled with glucose dehydrogenase
2008
Kurata, A.; Fujita, M.; Mowafy, A.M.; Kamachi, H.; Kurihara, T.; Esaki, N.
J. Biosci. Bioeng.
105
429-431
Links to other databases for 2-chloroacrylic acid
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