Ligand ecgonine methyl ester

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Basic Ligand Information

Molecular Structure
Picture of ecgonine methyl ester (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H17NO3
ecgonine methyl ester
QIQNNBXHAYSQRY-UYXSQOIJSA-N
Synonyms:
methyl (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]-octane-2-carboxylate, methyl (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, methyl-(1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]-octane-2-carboxylate, methyl ecgonine, methylecgonine

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methyl ecgonone + NADPH + H+ = methyl ecgonine + NADP+
show the reaction diagram
-
-
cocaine + H2O = ecgonine methyl ester + benzoate
show the reaction diagram
-
-

Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cocaine + H2O = ecgonine methyl ester + benzoate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.151
-
pH 6.8, temperature not specified in the publication

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.002673
-
substrate inhibition, pH 6.8, temperature not specified in the publication

References & Links

Links to other databases for ecgonine methyl ester

ChEBI
PubChem
ChEBI
PubChem