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BRENDA support

Ligand desmethylxanthohumol

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Basic Ligand Information

Molecular Structure
Picture of desmethylxanthohumol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C20H20O5
desmethylxanthohumol
FUSADYLVRMROPL-UXBLZVDNSA-N

Related pathways

Pathway Source
Pathways
MetaCyc
xanthohumol biosynthesis

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylallyl diphosphate + naringenin chalcone = diphosphate + desmethylxanthohumol
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol
show the reaction diagram
-
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + 4'-O-methyl-desmethylxanthohumol
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylallyl diphosphate + naringenin chalcone = diphosphate + desmethylxanthohumol
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive with respect to xanthohumol
-

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.018
-
pH 7.5, 30°C
0.023
-
pH 7.5, 30°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.002
-
pH 7.5, 30°C

References & Links

Links to other databases for desmethylxanthohumol

EXTERNAL LINKS