Ligand (R)-methylmalonyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of (R)-methylmalonyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C25H40N7O19P3S
(R)-methylmalonyl-CoA
MZFOKIKEPGUZEN-AGCMQPJKSA-N
Synonyms:
(2R)-methylmalonyl-CoA, (R)-2-methylmalonyl-CoA


Show all pahtways known for Show all BRENDA pathways known for (R)-methylmalonyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a long-chain acyl-CoA + 3 (R)-methylmalonyl-CoA + 6 NADPH + 6 H+ + holo-[mycolipanoate synthase] = mycolipanoyl-[mycolipanoate synthase] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O
show the reaction diagram
-
(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-methylmalonyl-CoA = (R)-methylmalonyl-CoA
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a long-chain acyl-CoA + 3 (R)-methylmalonyl-CoA + 6 NADPH + 6 H+ + holo-[mycolipanoate synthase] = mycolipanoyl-[mycolipanoate synthase] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O
show the reaction diagram
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(R)-2-methylmalonyl-CoA = succinyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-methylmalonyl-CoA = (R)-methylmalonyl-CoA
show the reaction diagram
-
-

3D Structure of Enzyme-Ligand-Complex (PDB) (4 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (14 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for (R)-methylmalonyl-CoA

ChEBI
PubChem
ChEBI
PubChem