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Ligand 2-deoxy-D-glucose[side 1] Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C6 H1 2 O5
2-deoxy-D-glucose[side 1]
VRYALKFFQXWPIH-PBXRRBTRSA-N
2-deoxy-D-glucose [side 1], 2-deoxyglucose[side 1]
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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[protein]-Npi-phospho-L-histidine + 2-deoxy-D-glucose[side 1] = [protein]-L-histidine + 2-deoxy-D-glucose 6-phosphate[side 2]
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Substrate in Enzyme-catalyzed Reactions (4 results)
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[protein]-Npi-phospho-L-histidine + 2-deoxy-D-glucose [side 1] = [protein]-L-histidine + 2-deoxy-D-glucose 6-phosphate[side 2]
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[protein]-Npi-phospho-L-histidine + 2-deoxy-D-glucose[side 1] = [protein]-L-histidine + 2-deoxy-D-glucose 6-phosphate[side 2]
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[protein]-Npi-phospho-L-histidine + 2-deoxyglucose[side 1] = [protein]-L-histidine + 2-deoxyglucose 6-phosphate[side 2]
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[protein]-Npi-phospho-L-histidine + 2-deoxy-D-glucose[side 1] = [protein]-L-histidine + 2-deoxy-D-glucose 6-phosphate[side 2]
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Enzyme Kinetic Parameters
KM Value (2 results)
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0.2
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at pH 7.5 and 25°C
0.2
-
at pH 7.5, temperature not specified in the publication
References & Links Literature References (4)
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Soluble sugar permeases of the phosphotransferase system in Escherichia coli: Evidence for two physically distinct forms of the proteins in vivo
2003
Aboulwafa, M.; Saier, M.H., Jr.
Mol. Microbiol.
48
131-141
Sugar transport by the bacterial phosphotransferase system. The glucose receptors of the Salmonella typhimurium phosphotransferase system
1982
Stock, J.; Waygood, E.; Meadow, N.; Postma, P.; Roseman, S.
J. Biol. Chem.
257
14543-14552
Contribution of the phosphoenolpyruvate: Mannose phosphotransferase system to carbon catabolite repression in Lactobacillus pentosus
2001
Chaillou, S.; Postma, P.; Pouwels, P.
Microbiology
147
671-679
Pel, the protein that permits lambda DNA penetration of Escherichia coli, is encoded by a gene in ptsM and is required for mannose utilization by the phosphotransferase system
1986
Williams, N.; Fox, D.; Shea, C.; Roseman, S.
Proc. Natl. Acad. Sci. USA
83
8934-8938
Links to other databases for 2-deoxy-D-glucose[side 1]