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Ligand phosphorylated histidine-containing protein

Basic Ligand Information

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.3.9

phosphoenolpyruvate + histidine-containing protein = pyruvate + phosphorylated histidine-containing protein

0

-

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.3.9

alpha-ketobutyrate + phosphorylated histidine-containing protein = phosphoenolbutyrate + histidine-containing protein

642510

-

2.7.3.9

beta-hydroxypyruvate + phosphorylated histidine-containing protein = ? + histidine-containing protein

642510

-

2.7.3.9

pyruvate + phosphorylated histidine-containing protein = phosphoenolpyruvate + histidine-containing protein

642504, 642510, 642514, 641887, 642497, 642505, 642511, 642520, 642500

-

2.7.3.9

3 entries

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.3.9

phosphoenolpyruvate + histidine-containing protein = pyruvate + phosphorylated histidine-containing protein

0, 642508, 642504

-

Enzyme Kinetic Parameters

References & Links

Literature References (10)

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Show Reference (10 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

641887

11551914

Substitution of aspartate and glutamate for active center histidines in the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system maintain phosphotransfer potential

2001

Napper, S.; Brokx, S.J.; Pally, E.; Kindrachuk, J.; Delbaere, L.T.J.; Waygood, E.B.

J. Biol. Chem.

276

41588-41593

642497

8051118

Sugar transport by the bacterial phosphotransferase system. Characterization of the Escherichia coli enzyme I monomer/dimer equilibrium by fluorescence anisotropy

1994

Chauvin, F.; Brand, L.; Roseman, S.

J. Biol. Chem.

269

20263-20269

642500

3922407

Phosphoenolpyruvate-dependent protein kinase enzyme I of Streptococcus faecalis: purification and properties of the enzyme and characterization of its active center

1985

Alpert, C.A.; Frank, R.; Stüber, K.; Deutscher, J.; Hengstenberg, W.

Biochemistry

24

959-964

642504

6754730

Sugar transport by the bacterial phosphotransferase system. Phosphoryl transfer reactions catalyzed by enzyme I of Salmonella typhimurium

1982

Weigel, N.; Kukuruzinska, M.A.; Nakazawa, A.; Waygood, E.B.; Roseman, S.

J. Biol. Chem.

257

14477-14491

642505

7049236

Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system: role of divalent metals in the dimerization and phosphorylation of enzyme I

1982

Hoving, H.; Koning, J.H.; Robillard, G.T.

Biochemistry

21

3128-3136

642508

-

Enzyme I from Salmonella typhimurium

1982

Kukuruzinska, M.A.; Weigel, N.; Waygood, E.B.

Methods Enzymol.

90

431-436

642510

6997300

Phosphoryl exchange reaction catalyzed by enzyme I of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. Kinetic characterization

1980

Saier, M.H.; Schmidt, M.R.; Lin, P.

J. Biol. Chem.

255

8579-8584

642511

6986909

Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system. Evidence that the dimer is the active form of enzyme I

1980

Misset, O.; Brouwer, M.; Robillard, G.T.

Biochemistry

19

883-890

642514

187249

The bacterial phosphoenolpyruvate: sugar phosphotransferase system

1976

Postma, P.W.; Roseman, S.

Biochim. Biophys. Acta

457

213-257

642520

8692938

The N-terminal domain of Escherichia coli enzyme I of the phosphoenolpyruvate/glycose phosphotransferase system: molecular cloning and characterization

1996

Chauvin, F.; Fomenkov, A.; Johnson, C.R.; Roseman, S.

Proc. Natl. Acad. Sci. USA

93

7028-7031

Links to other databases for phosphorylated histidine-containing protein

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