Ligand [Wnt3a]-L-serine
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Basic Ligand Information
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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(9Z)-hexadec-9-enoyl-CoA + [Wnt3a]-L-serine = CoA + [Wnt3a]-O-(9Z)-hexadec-9-enoyl-L-serine
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Substrate in Enzyme-catalyzed Reactions (1 result)
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(9Z)-hexadec-9-enoyl-CoA + [Wnt3a]-L-serine = CoA + [Wnt3a]-O-(9Z)-hexadec-9-enoyl-L-serine
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Enzyme Kinetic Parameters
References & Links
Literature References (4)
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Monounsaturated fatty acid modification of Wnt p+rotein: its role in Wnt secretion
2006
Takada, R.; Satomi, Y.; Kurata, T.; Ueno, N.; Norioka, S.; Kondoh, H.; Takao, T.; Takada, S.
Dev. Cell
11
791-801
Porcupine-mediated lipid-modification regulates the activity and distribution of Wnt proteins in the chick neural tube
2007
Galli, L.; Barnes, T.; Secrest, S.; Kadowaki, T.; Burrus, L.
Development
134
3339-3348
Precise regulation of porcupine activity is required for physiological Wnt signaling
2012
Proffitt, K.D.; Virshup, D.M.
J. Biol. Chem.
287
34167-34178
Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine
2014
Gao, X.; Hannoush, R.N.
Nat. Chem. Biol.
10
61-68
Links to other databases for [Wnt3a]-L-serine