Ligand 4-methylbenzaldehyde

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 4-methylbenzaldehyde (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H8O
4-methylbenzaldehyde
FXLOVSHXALFLKQ-UHFFFAOYSA-N
Synonyms:
4-methyl-benzaldehyde, 4-methyl benzaldehyde, 4-tolualdehyde, p-methyl-benzaldehyde, p-methylbenzaldehyde, p-tolualdehyde

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (27 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-methylbenzaldehyde + NADPH + H+ = 4-methylbenzyl alcohol + NADP+
show the reaction diagram
-
p-methylbenzaldehyde + NADPH = p-methylbenzyl alcohol + NADP+
show the reaction diagram
-
4-methylbenzaldehyde + H2O + O2 = 4-methylbenzoate + H2O2
show the reaction diagram
-
4-methylbenzaldehyde + NAD+ + H2O = 4-methylbenzoate + NADH
show the reaction diagram
-
4-methylbenzaldehyde + NAD+ + H2O = 4-methylbenzoate + NADH + H+
show the reaction diagram
-
4-methylbenzaldehyde + 1-hydroxypropan-2-one = (3R,4S)-3,4-dihydroxy-4-(4-methylphenyl)butan-2-one
show the reaction diagram
-
glycine + 4-methylbenzaldehyde = (2R,3S)-2-amino-3-hydroxy-3-(4-methylphenyl)propanoic acid + (2R,3R)-2-amino-3-hydroxy-3-(4-nitrophenyl)propanoic acid
show the reaction diagram
-
p-tolualdehyde + pyruvate = (3E)-4-(4-methylphenyl)-2-oxobut-3-enoate + H2O
show the reaction diagram
-
cyanide + 4-methylbenzaldehyde = (2S)-(4-methylphenyl)(hydroxy)ethanenitrile
show the reaction diagram
-
4-methylbenzaldehyde + HCN + H2O = ? + H2O
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-methylbenzyl alcohol + NADP+ = 4-methylbenzaldehyde + NADPH
show the reaction diagram
-
-
4-methylbenzyl alcohol + NAD+ = 4-methylbenzaldehyde + NADH
show the reaction diagram
-
-
4-methylbenzyl alcohol + O2 = 4-methylbenzaldehyde + H2O2
show the reaction diagram
-
4-Methylbenzoate + reduced carbamoyl methyl viologen = 4-Methylbenzaldehyde + carbamoyl methyl viologen
show the reaction diagram
-
-
4-methylbenzylamine + O2 + H2O = 4-methylbenzaldehyde + NH3 + H2O2
show the reaction diagram
-
-
1-(4-methylphenyl)methanamine + H2O + O2 = 4-methylbenzaldehyde + NH3 + H2O2
show the reaction diagram
-
-
4-methyl-benzoylformic acid = 4-methylbenzaldehyde + CO2
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition
-
substrate inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3
-
enzyme ALDH-2
5520
-
pH 4.2, 22°C

KM Value (14 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.3
-
-
0.04
-
pH 7.0
0.000017
-
enzyme ALDH-2
0.53
-
-
0.53
-
in 100 mM glycine-NaOH (pH 9.2), at 25°C
1.4
-
pH 7.0, 30°C
5.4
-
pH 4.2, 22°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.003
-
apparent Ki-value, pH 9.6, temperature not specified in the publication

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.12
-
-

References & Links

Links to other databases for 4-methylbenzaldehyde

ChEBI
PubChem
-
PubChem