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Ligand DL-phosphoserine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.3.3

O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate

750864

-

Substrate in Enzyme-catalyzed Reactions (5 results)

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Show Substrate (5 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.3.1

O-phospho-DL-serine + H2O = DL-serine + phosphate

654022

-

3.1.3.2

O-phospho-DL-serine + H2O = ?

651517

-

3.1.3.2

O-phospho-DL-serine + H2O = D-serine + phosphate

677423

-

3.1.3.3

DL-phosphoserine + H2O = DL-Ser + phosphate

81050, 81043, 81051, 81049, 81052

-

3.1.3.3

O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate

750864

-

3.1.3.2

2 entries

3.1.3.3

2 entries

Enzyme Kinetic Parameters

K_M Value (3 results)

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Show KM Value (3 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.1.3.3

0.05

-

unassociated enzyme form

81043

3.1.3.3

0.1

-

associated enzyme form

81043

3.1.3.3

0.11

-

-

81050

3.1.3.3

3 entries

References & Links

Literature References (9)

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Show Reference (9 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

81043

4374244

O-Phosphoserine phosphatase from bovine brain and kidney. High molecular weight forms occurring during the purification

1974

Paoli, A.; Guiraud, P.; Brunel, C.

Biochim. Biophys. Acta

370

487-497

81049

-

Regulation and routes of biosynthesis of serine and arginine in Methylophilus methylotrophus AS1

1987

Kearney, P.; Holloway, B.W.

FEMS Microbiol. Lett.

42

109-112

81050

13610904

Metabolism of phosphoserine. II. Purification and properties of O-phosphoserine phosphatase

1959

Neuhaus, F.C.; Byrne, W.L.

J. Biol. Chem.

234

113-121

81051

24241741

Enzymes of serine and glycine metabolism in leaves and non-photosynthetic tissues of Pisum sativum L.

1986

Walton, N.J.; Woolhouse, H.W.

Planta

167

119-128

81052

5370284

Serine biosynthesis in Desulfovibrio desulfuricans

1969

Germano, G.J.; Andersen, K.E.

J. Bacteriol.

99

893-894

651517

-

Purification and properties of an acid phosphatase from Lactobacillus curvatus DPC2024

2000

Magboul, A.A.A.; McSweeney, P.L.H.

Int. Dairy J.

9

849-855

654022

-

Purification and properties of alkaline phosphatase with protein phosphatase activity from Saccharomyces cerevisiae

2000

Galabova, D.; Tuleva, B.; Vasileva-Tonkova, E.; Christova, N.

Z. Naturforsch. C

55

588-593

677423

-

Optimization of the kinetic resolution of the DL-phosphomonoesters of threonine and serine by random mutagenesis of the acid phosphatase from Salmonella enterica

2007

van Herk, T.; Hartog, A.F.; Ruijssenaars, H.J.; Kerkman, R.; Schoemaker, H.E.; Wever, R.

Adv. Synth. Catal.

349

1349-1352

750864

30248937

Hanks-type Serine/threonine protein kinases and phosphatases in bacteria roles in signaling and adaptation to various environments

2018

Janczarek, M.; Vinardell, J.M.; Lipa, P.; Karas, M.

Int. J. Mol. Sci.

19

2872-2901

Links to other databases for DL-phosphoserine

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Show Links (1 entry)

ChEBI

PubChem