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0.038
-
mutant FVIIaVEAY-sTF, 210 nM
0.0493
-
wild type enzyme, in the presence of soluble tissue factor (1-219), at pH 7.4 and 25°C
0.05
-
mutant FVIIaIIa-sTF, 210 nM
0.077
-
wild type FVIIa-sTF, 210 nM
0.1
-
wild-type + soluble tissue factor for induced allosteric activation of factor VIIa
0.116
-
pH 8.0, wild-type enzyme, chromozym tPA as substrate with addition of tissue factor
0.124
-
pH 8.0, mutant enzyme V21N/E154I/M156Q, chromozym tPA as substrate with addition of tissue factor
0.177
-
mutant FVIIaVEAY, 10 nM
0.226
-
mutant FVIIaIIa, 25 nM
0.317
-
pH 8.0, mutant enzyme V21N/E154I/M156Q, chromozym tPA as substrate without addition of tissue factor
0.7
-
mutant G372 + soluble tissue factor for induced allosteric activation of factor VIIa
1.41
-
wild type FVIIa, 100 nM
1.485
-
wild type enzyme, in the absence of soluble tissue factor (1-219), at pH 7.4 and 25°C
3.2
-
in 50 mM HEPES, pH 7.4, with 0.1 M NaCl, 5 mM CaCl2, 0.1% (w/v) bovine serum albumin, and 0.01% Tween 80, at 25°C
0.0000211
-
mutant enzyme Y143A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000245
-
mutant enzyme K192E, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000362
-
mutant enzyme R3704A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000396
-
mutant enzyme E98V, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000416
-
mutant enzyme E98A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000419
-
mutant enzyme Y5901V, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000497
-
mutant enzyme Y5901A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000513
-
wild type enzyme, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000714
-
mutant enzyme K192R, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0000739
-
mutant enzyme I151A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.000079
-
mutant enzyme K192Q, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.0001529
-
mutant enzyme K192A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C
0.06
-
37°C, recombinant wild-type enzyme, versus substrate S-2366
0.085
-
37°C, recombinant peptide FXI/E361-V607, versus substrate S-2366
0.086
-
37°C, recombinant peptide FXI/E361-V607, versus substrate factor IX
0.095
-
37°C, recombinant wild-type enzyme, versus substrate factor IX
0.05697
-
22°C, pH not specified in the publication
0.085
-
pH 8.0, 25°C, with wild-type enzyme
0.051
-
full-length plasmin, in phosphate buffered saline, pH 7.4, at 25°C
0.061
-
truncated delta-plasmin, in phosphate buffered saline, pH 7.4, at 25°C
0.0395
-
pH 7.4, 37°C, mature uPA
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Spermosin
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Purification of xanthine oxidase from bovine milk by affinity chromatography with a novel gel
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Molecular basis of enhanced activity in factor VIIa-trypsin variants conveys insights into tissue factor-mediated allosteric regulation of factor VIIa activity
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Molecular basis of enhanced activity in factor VIIa-trypsin variants conveys insights into tissue factor-mediated allosteric regulation of factor VIIa activity
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