Ligand 5-chloro-L-kynurenine

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Basic Ligand Information

Molecular Structure
Picture of 5-chloro-L-kynurenine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H11ClN2O3
5-chloro-L-kynurenine
VCCXKKFHLAJBJJ-QMMMGPOBSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-chloro-L-kynurenine + NADPH + H+ + O2 = 5-chloro-3-hydroxy-L-kynurenine + NADP+ + H2O
show the reaction diagram
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5-chloro-L-kynurenine + H2O = 5-chloroanthranilate + L-alanine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
kynurenine + FADH2 + chloride + O2 + H+ = 5-chloro-L-kynurenine + FAD + 2 H2O
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.8
-
pH and temperature not specified in the publication

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.002
-
pH and temperature not specified in the publication

References & Links

Links to other databases for 5-chloro-L-kynurenine

ChEBI
PubChem
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PubChem