print visible entries

print all entries

Ligand 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

4.2.1.106

7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA = 3-oxochola-4,6-dien-24-oyl-CoA

735231

-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.3.1.115

7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+

0

-

Substrate in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

4.2.1.106

7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA = 3-oxochola-4,6-dien-24-oyl-CoA

735231

-

Product in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.3.1.115

7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+

0

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (4 results)

top print hide

Show Turnover Number (4 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

4.2.1.106

12.6

-

25°C in 20 mM Tris-HCl, pH 7.3

735231

4.2.1.106

15

-

25°C in 20 mM Tris-HCl, pH 7.3

735231

4.2.1.106

22.2

-

25°C in 20 mM Tris-HCl, pH 7.3

735231

4.2.1.106

98

-

25°C in 20 mM Tris-HCl pH 7.3

735231

4.2.1.106

4 entries

K_M Value (4 results)

top print hide

Show KM Value (4 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

4.2.1.106

1.2

-

25°C in 20 mM Tris-HCl, pH 7.3

735231

4.2.1.106

4

-

25°C in 20 mM Tris-HCl pH 7.3

735231

4.2.1.106

11.4

-

25°C in 20 mM Tris-HCl, pH 7.3

735231

4.2.1.106

208

-

25°C in 20 mM Tris-HCl, pH 7.3

735231

4.2.1.106

4 entries

References & Links

Literature References (1)

top print hide

Show Reference (1 entry)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

735231

26650892

Structure and functional characterization of a bile acid 7alpha dehydratase BaiE in secondary bile acid synthesis

2016

Bhowmik, S.; Chiu, H.P.; Jones, D.H.; Chiu, H.J.; Miller, M.D.; Xu, Q.; Farr, C.L.; Ridlon, J.M.; Wells, J.E.; Elsliger, M.A.; Wilson, I.A.; Hylemon, P.B.; Lesley, S.A.

Proteins

84

316-331

Links to other databases for 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA

top print hide

Show Links (1 entry)

ChEBI

PubChem

-