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BRENDA support

Ligand 2-methyl-DL-serine

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Basic Ligand Information

Molecular Structure
Picture of 2-methyl-DL-serine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H9NO3
2-methyl-DL-serine
CDUUKBXTEOFITR-UHFFFAOYSA-N
Synonyms:
2-methyl-D,L-serine, 2-methylserine, alpha-methyl-DL-serine, alpha-Methylserine, DL-2-methylserine, DL-alpha-Methylserine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-methyl-DL-serine + NADP+ = 2-amino-2-methyl-3-oxopropanoic acid + NADPH
show the reaction diagram
-
2-methyl-D,L-serine + NAD+ = ?
show the reaction diagram
-
alpha-methylserine + tetrahydrofolate = D-alanine + 5,10-methylenetetrahydrofolate
show the reaction diagram
-
tetrahydrofolate + 2-methyl-DL-serine = 5,10-methylenetetrahydrofolate + D-alanine + H2O
show the reaction diagram
-
diphosphate + alpha-methylserine = phosphate + alpha-methyl-O-phospho-L-serine
show the reaction diagram
-
CDP-ethanolamine + DL-alpha-methylserine = ?
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive to L-serine
-
inhibition of D- and L-transamination of D-alanine to alpha-ketoglutarate, weak
-

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
83
-
-
1.5
-
pH 7.5

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 2-methyl-DL-serine

ChEBI
PubChem
ChEBI
PubChem