print visible entries

print all entries

Ligand (+)-5-chloromuconolactone

Basic Ligand Information

Molecular Structure

Related pathways

Show all BRENDA pathways known for (+)-5-chloromuconolactone

close all tables

open all tables

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

top print hide

Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.5.1.7

(+)-5-Chloromuconolactone = trans-4-Carboxymethylenebut-2-en-4-olide + Cl-

3760, 3656

-

5.5.1.7

5-chloromuconolactone = trans-dienelactone

767444

-

5.5.1.7

2 entries

Product in Enzyme-catalyzed Reactions (5 results)

top print hide

Show Product (5 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.5.1.1

2-chloro-cis,cis-muconate = (+)-2-chloromuconolactone + (+)-5-chloromuconolactone

649348

-

5.5.1.1

2-chloro-cis,cis-muconate = 5-chloromuconolactone + 2-chloromuconolactone

653843, -

-

5.5.1.1

3-Chloro-cis,cis-muconate = 5-Chloromuconolactone

3656, -

-

5.5.1.7

2-Chloro-cis,cis-muconate = 5-Chloromuconolactone

650268, 3656

-

5.5.1.7

2-chloromuconate = 5-chloromuconolactone

-

-

5.5.1.1

3 entries

5.5.1.7

2 entries

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

top print hide

Show Turnover Number (1 entry)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

5.5.1.7

24.7

-

-

3760

K_M Value (1 result)

top print hide

Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

5.5.1.7

0.805

-

-

3760

References & Links

Literature References (6)

top print hide

Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

3656

7751292

Characterization of muconate and chloromuconate cycloisomerase from Rhodococcus erythropolis 1CP: indications for functionally convergent evolution among bacterial cycloisomerases

1995

Solyanikova, I.P.; Maltseva, O.V.; Vollmer, M.D.; Golovleva, L.A.; Schlömann, M.

J. Bacteriol.

177

2821-2826

3760

7751312

Conversion of 2-chloro-cis,cis-muconate and its metabolites 2-chloro- and 5-chloromuconolactone by chloromuconate cycloisomerases of pJP4 and pAC27

1995

Vollmer, M.D.; Schlömann, M.

J. Bacteriol.

177

2938-2941

649348

9726873

Substrate specificity of and product formation by muconate cycloisomerases: an analysis of wild-type enzymes and engineered variants

1998

Vollmer, M.D.; Hoier, H.; Hecht, H.J.; Schell, U.; Groning, J.; Goldman, A.; Schlomann, M.

Appl. Environ. Microbiol.

64

3290-3299

650268

11405892

Enzymes of a new modified ortho-pathway utilizing 2-chlorophenol in Rhodococcus opacus 1CP

2001

Moiseeva, O.V.; Belova, O.V.; Solyanikova, I.P.; Schlomann, M.; Golovleva, L.A.

Biochemistry (Moscow)

66

548-555

653843

10336378

Structural basis for the activity of two muconate cycloisomerase variants toward substituted muconates

1999

Schell, U.; Helin, S.; Kajander, T.; Schlomann, M.; Goldman, A.

Proteins Struct. Funct. Genet.

34

125-136

767444

-

Pathways of 3-chlorobenzoate degradation by Rhodococcus opacus strains 1CP and 6a

2019

Solyanikova, I.; Emelyanova, E.; Shumkova, E.; Travkin, V.

Microbiology (Russian Federation)

88

563-572

Links to other databases for (+)-5-chloromuconolactone

top print hide

Show Links (1 entry)