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BRENDA support

Ligand ubiquinone-8

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Basic Ligand Information

Molecular Structure
Picture of ubiquinone-8 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C49H74O4
ubiquinone-8
ICFIZJQGJAJRSU-SGHXUWJISA-N
Synonyms:
ubiquinone Q8

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[DsbA protein] with reduced L-cysteine residues + ubiquinone Q8 = [DsbA protein] carrying a disulfide bond + ubiquinol Q8
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
succinate + ubiquinone-8 = fumarate + ubiquinol-8
show the reaction diagram
-
NADH + ubiquinone-8 = NAD+ + ubiquinol-8
show the reaction diagram
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NADH + H+ + ubiquinone-8 + n Na+/in = NAD+ + ubiquinol-8 + n Na+/out
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 ubiquinol-8 + O2 = 2 ubiquinone-8 + 2 H2O
show the reaction diagram
-
-

Enzyme Cofactor/Cosubstrate (13 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
efficient, N-terminally truncated protein
-
0.2 mM quinone stimulates reaction with D-alanine and oxidized 2,6-dichloroindophenol 2fold
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3D Structure of Enzyme-Ligand-Complex (PDB) (13 results)

Enzyme Kinetic Parameters

References & Links

Links to other databases for ubiquinone-8

ChEBI
PubChem
ChEBI
PubChem