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Ligand myristoyl-L-carnitine Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 1 H4 1 NO4
myristoyl-L-carnitine
PSHXNVGSVNEJBD-LJQANCHMSA-N
L-myristoylcarnitine, L-tetradecanoylcarnitine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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myristoyl-L-carnitine + CoA = myristoyl-CoA + L-carnitine
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myristoyl-L-carnitine + H2O = myristic acid + L-carnitine
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Product in Enzyme-catalyzed Reactions (3 results)
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tetradecanoyl-CoA + L-carnitine = CoA + L-tetradecanoylcarnitine
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myristoyl-CoA + L-carnitine = myristoyl-L-carnitine + CoA
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myristoyl-CoA + L-carnitine = CoA + L-myristoylcarnitine
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links Literature References (5)
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Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function
1985
Mentlein, R.; Reuter, G.; Heymann, E.
Arch. Biochem. Biophys.
240
801-810
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Comparison of the carnitine acyltransferase activities from rat liver peroxisomes and microsomes
1976
Markwell, M.A.K.; Tolbert, N.E.; Bieber, L.L.
Arch. Biochem. Biophys.
176
479-488
Isolation and purification of mitochondrial carnitine octanoyltransferase activities from beef heart
1981
Clarke, P.R.H.; Bieber, L.L.
J. Biol. Chem.
256
9861-9868
Fatty acyl group transport into mitochondria: carnitine palmitoyl transferases EC 2.3.1.23 and the carnitine-acylcarnitine translocase
1979
Halperin, M.L.; Pande, S.V.
Methods Enzymol.
56
368-378
Purification, characterization and partial amino acid sequences of carnitine palmitoyl-transferase from human liver
1990
Finocchiaro, G.; Colombo, I.; DiDonato, S.
FEBS Lett.
274
163-166
Links to other databases for myristoyl-L-carnitine