Ligand 6-demethylmitomycin A
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Basic Ligand Information
Molecular Structure

C15H17N3O6
6-demethylmitomycin A
WXARXUKKMUUSGN-WUDYKRTCSA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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S-adenosyl-L-methionine + 6-demethylmitomycin A = S-adenosyl-L-homocysteine + mitomycin A
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Hydroxyquinone O-methylation in mitomycin biosynthesis
2007
Grüschow, S.; Chang, L.C.; Mao, Y.; Sherman, D.H.
J. Am. Chem. Soc.
129
6470-6476
Structural characterization of the mitomycin 7-O-methyltransferase
2011
Singh, S.; Chang, A.; Goff, R.D.; Bingman, C.A.; Grüschow, S.; Sherman, D.H.; Phillips, G.N. Jr.; Thorson, J.S.
Proteins
79
2181-2188
Links to other databases for 6-demethylmitomycin A