Ligand (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C41H64N7O17P3S
(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA
JWZLRYCDDXHXDL-LCMHIRPZSA-N
Synonyms:
(5Z,8Z,11Z,14Z,17Z) -5,8,11,14,17-icosapentaenoyl-CoA, (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-CoA, 5,8,11,14,17-eicosapentaenoyl-CoA, eicosapentaenoyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
eicosapentaenoyl-CoA + 1-acyl-lysophosphatidic acid = CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidic acid
show the reaction diagram
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eicosapentaenoyl-CoA + 1-acyl-lysophosphatidylinositol = CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidylinositol
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + ferrocytochrome b5 + O2 + H+ = (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-CoA + ferricytochrome b5 + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
eicosapentaenoyl-CoA + O2 = ?
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(5Z,8Z,11Z,14Z,17Z) -5,8,11,14,17-icosapentaenoyl-CoA + oxidized electron transfer flavoprotein = ? + reduced electron transfer flavoprotein
show the reaction diagram
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eicosapentaenoyl-CoA + sn-glycerol 3-phosphate = CoA + 1-eicosapentaenoyl-sn-glycerol 3-phosphate
show the reaction diagram
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eicosapentaenoyl-CoA + 1,2-diacyl-sn-glycerol = CoA + 1,2-diacyl-3-eicosapentaenoylglycerol
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eicosapentaenoyl-CoA + 1-acyl-lysophosphatidylinositol = CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidylinositol
show the reaction diagram
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eicosapentaenoyl-CoA + H2O = CoA + eicosapentaenoate
show the reaction diagram
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eicosapentaenoyl-CoA + H2O = CoA + eicosapentaenoate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 5,8,11,14,17-eicosapentaenoic acid + CoA = ATP + diphosphate + 5,8,11,14,17-eicosapentaenoyl-CoA
show the reaction diagram
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ATP + eicosapentaenoate + CoA = AMP + diphosphate + eicosapentaenoyl-CoA
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

ChEBI
PubChem
ChEBI
PubChem