Ligand D-galactaro-1,5-lactone

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Basic Ligand Information

Molecular Structure
Picture of D-galactaro-1,5-lactone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O7
D-galactaro-1,5-lactone
YLKFQNUGXOLRNI-KXMYSMCESA-N
Synonyms:
D-galactarolactone


Show all pahtways known for Show all BRENDA pathways known for D-galactaro-1,5-lactone

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-galactaro-1,5-lactone = D-galactaro-1,4-lactone
show the reaction diagram
-
D-galactarolactone = 3-deoxy-2-dehydro-L-threo-hexarate
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-D-galacturonate + NAD+ = D-galactaro-1,5-lactone + NADH + H+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-galactaro-1,5-lactone = D-galactaro-1,4-lactone
show the reaction diagram
-
D-galactarolactone = 3-deoxy-2-dehydro-L-threo-hexarate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-D-galacturonate + NAD+ = D-galactaro-1,5-lactone + NADH + H+
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
noncompetitve versus NAD+ and beta-D-glucuronate

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
16
-
mutant enzyme N240D, pH and temperature not specified in the publication

References & Links

Links to other databases for D-galactaro-1,5-lactone

ChEBI
PubChem
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PubChem