Ligand 7alpha,12alpha-dihydroxy-4-cholesten-3-one

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Basic Ligand Information

Molecular Structure
Picture of 7alpha,12alpha-dihydroxy-4-cholesten-3-one (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C27H44O3
7alpha,12alpha-dihydroxy-4-cholesten-3-one
UQPYXHJTHPHOMM-NIBOIBLTSA-N
Synonyms:
(7alpha,12alpha)-7,12-dihydroxy-4-cholesten-3-one, 4-cholesten-7alpha,12alpha-diol-3-one, 7alpha,12alpha-dihydroxycholest-4-en-3-one, DELTA 4-cholestene-7alpha,12alpha-diol-3-one


Show all pahtways known for Show all BRENDA pathways known for 7alpha,12alpha-dihydroxy-4-cholesten-3-one

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
DELTA 4-cholestene-7alpha,12alpha-diol-3-one + NADPH + H+ = 5beta-cholestane-7alpha,12alpha-diol-3-one + NADP+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0128
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KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0122
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-

References & Links

Links to other databases for 7alpha,12alpha-dihydroxy-4-cholesten-3-one

ChEBI
PubChem
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PubChem