Ligand 2,3-Butanediol

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Basic Ligand Information

Molecular Structure
Picture of 2,3-Butanediol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H10O2
2,3-Butanediol
JARKCYVAAOWBJS-UHFFFAOYSA-N
Synonyms:
2,3-Butandiol, 2,3-Butylene glycol, 3-hydroxy-2-butanol, Butan-2,3-diol, butane-2,3-diol, DL-2,3-butanediol, rac-butan-2,3-diol

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetoin + NAD(P)+ = 2,3-butanediol + NAD(P)H + H+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (29 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
butane-2,3-diol + NAD+ = ? + NADH
show the reaction diagram
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2,3-butanediol + NADP+ = ?
show the reaction diagram
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2,3-butanediol + NADP+ = ?
show the reaction diagram
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2,3-butanediol + NADP+ = 3-hydroxybutan-2-one + NADPH
show the reaction diagram
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2,3-butanediol + NADP+ = acetoin + NADPH + H+
show the reaction diagram
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2,3-butanediol + NAD+ = ? + NADH
show the reaction diagram
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2,3-butanediol + NAD+ = ? + NADH
show the reaction diagram
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2,3-butanediol + NAD+ = ?
show the reaction diagram
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2,3-butylene glycol + NADP+ = ?
show the reaction diagram
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2,3-butanediol + NAD+ = 3-hydroxybutane-2-one + NADH
show the reaction diagram
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2,3-butanediol + NAD+ = ? + NADH
show the reaction diagram
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butan-2,3-diol + NAD+ = ?
show the reaction diagram
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rac-butan-2,3-diol + NADPH + H+ = ?
show the reaction diagram
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2,3-butanediol + NAD+ = ? + NADH
show the reaction diagram
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2,3-butanediol + ferricytochrome c = ?
show the reaction diagram
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2,3-butanediol + reduced 2,6-dichlorophenolindophenol = ? + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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2,3-butanediol + pyrroloquinoline quinone = ?
show the reaction diagram
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2,3-butanediol + ferricyanide = 3-hydroxybutan-2-one + ferrocyanide
show the reaction diagram
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2,3-butanediol = methyl ethyl ketone
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-butanedione + NAD(P)H = 2,3-butanediol + NAD(P)+
show the reaction diagram
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acetoin + NADPH + H+ = 2,3-butanediol + NADP+
show the reaction diagram
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acetoin + NADH + H+ = 2,3-butanediol + NAD+
show the reaction diagram
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acetoin + NAD(P)+ = 2,3-butanediol + NAD(P)H + H+
show the reaction diagram
-
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acetoin + NAD(P)H + H+ = 2,3-butanediol + NAD(P)+
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates
-
activates
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isoform AC6 shows about 30% stimulation of activity with 100 mM 2,3-butanediol, isoform AC7 shows about 35% stimulation of activity with 100 mM 2,3-butanediol, isoform AC9 shows about 41% stimulation of activity with 100 mM 2,3-butanediol
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
more than2 mM, 50% inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (22 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
26
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pH 7.5, 37°C

KM Value (27 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
18
-
pH 7.5, 37°C
0.0238
-
-
0.64
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References & Links

Links to other databases for 2,3-Butanediol

ChEBI
PubChem
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PubChem