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2,4-diamino-n-butyric acid, 2,4-diaminobutanoate, 2,4-diaminobutyrate, diaminobutyric acid, DL-2,4-diaminobutanoate, DL-2,4-diaminobutryic acid, DL-2,4-diaminobutyric acid
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0.008
-
synaptosomal enzyme, pH 8.0
0.013
-
cytoplasmic enzyme, pH 8.0
11.5
-
pH 7.8, 35°C, competitive inhibition with respect to 2-oxoglutarate
190
-
pH 7.8, 35°C, noncompetitive inhibition with respect to delta-aminovalerate
0.0046
-
pH 8.5, 25°C, recombinant wild-type enzyme
0.0046
-
recombinant wild-type, pH 8.5, 25°C
0.032
-
pH 8.5, 25°C, recombinant mutant Y187F
0.095
-
recombinant mutant H225A, pH 8.5, 25°C
0.098
-
recombinant mutant H225Q, pH 8.5, 25°C
0.1
-
pH 8.5, 25°C, recombinant mutant N226D
0.27
-
pH 8.5, 25°C, recombinant mutant S162A
2
-
pH 8.5, 25°C, recombinant mutant Y160F
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-
Carnosine synthetase (chick muscle)
1971
Kalyankar, G.D.; Meister, A.
Methods Enzymol.
17
102-105
Enzymatic synthesis of carnosine and related beta-alanyl and gamma-aminobutyryl peptides
1959
Kalyankar, G.D.; Meister, A.
J. Biol. Chem.
234
3210-3218
Ornithine carbamoyltransferase from Escherichia coli W. Purification, structure and steady-state kinetic analysis
1976
Legrain, C.; Stalon, V.
Eur. J. Biochem.
63
289-301
-
Biosynthesis of beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, the Lathyrus sativus neurotoxin
1970
Malathi, K.; Padmanaban, G.; Sarma, P.S.
Phytochemistry
9
1603-1610
The inhibition by substrate analogues of gamma-aminobutyrate aminotransferase from mitochondria of different subcellular fractions of rat brain
1977
Tunnicliff, G.; Ngo, T.T.; Rojo-Ortega, J.M.; Barbeau, A.
Can. J. Biochem.
55
479-484
Purification and partial characterization of 4-aminobutyrate:2-oxoglutarate aminotransferase from sheep brain and locust ganglia
1988
Jeffery, D.; Rutherford, D.M.; Witzman, P.D.J.; Lunt, G.G.
Biochem. J.
249
795-799
Cysteine sulfinate aminotransferase and aspartate aminotransferase isoenzymes of rat brain. Purification, characterization, and further evidence for identity
1980
Recasens, M.; Benezra, R.; Mandel, P.
Biochemistry
19
4583-4589
Candida delta-aminovalerate: alpha-ketoglutarate aminotransferase: purification and enzymologic properties
1986
Der Garabedian, P.A.
Biochemistry
25
5507-5512
Kinetic analysis of the L-L-ornithine transcarbamoylase from Pseudomonas savastanoi pv. phaseolicola that is resistant to the transition state analogue (R)-N delta-(N'-sulfodiaminophosphinyl)-L-L-ornithine
2005
Templeton, M.D.; Reinhardt, L.A.; Collyer, C.A.; Mitchell, R.E.; Cleland, W.W.
Biochemistry
44
4408-4415
Coexpression, purification and characterization of the E and S subunits of coenzyme B(12) and B(6) dependent Clostridium sticklandii D-ornithine aminomutase in Escherichia coli
2004
Chen, H.P.; Hsui, F.C.; Lin, L.Y.; Ren, C.T.; Wu, S.H.
Eur. J. Biochem.
271
4293-4297
-
The presence of L-2,4-diaminobutyric acid decarboxylase activity in Vibrio species: a new biosynthetic pathway for 1,3-diaminopropane
1986
Yamamoto, S.; Suemoto, Y.; Seito, Y.; Nakao, H.; Shinoda, S.
FEMS Microbiol. Lett.
35
289-293
Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase
2008
Wolthers, K.R.; Rigby, S.E.; Scrutton, N.S.
J. Biol. Chem.
283
34615-34625
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase
2010
Wolthers, K.R.; Levy, C.; Scrutton, N.S.; Leys, D.
J. Biol. Chem.
285
13942-13950
Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface
2012
Chittori, S.; Savithri, H.S.; Murthy, M.R.
BMC Struct. Biol.
12
24
Role of histidine 225 in adenosylcobalamin-dependent ornithine 4,5-aminomutase
2012
Makins, C.; Miros, F.N.; Scrutton, N.S.; Wolthers, K.R.
Bioorg. Chem.
40
39-47
Optimal electrostatic interactions between substrate and protein are essential for radical chemistry in ornithine 4,5-aminomutase
2017
Makins, C.; Whitelaw, D.A.; McGregor, M.; Petit, A.; Mothersole, R.G.; Prosser, K.E.; Wolthers, K.R.
Biochim. Biophys. Acta
1865
1077-1084
Glutamate 338 is an electrostatic facilitator of C-Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase
2015
Menon, B.R.; Menon, N.; Fisher, K.; Rigby, S.E.; Leys, D.; Scrutton, N.S.
FEBS J.
282
1242-1255
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