Ligand (+)-dihydrokaempferol

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Basic Ligand Information

Molecular Structure
Picture of (+)-dihydrokaempferol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H12O6
(+)-dihydrokaempferol
PADQINQHPQKXNL-LSDHHAIUSA-N
Synonyms:
(+)-2,3-dihydrokaempferol, (+)-trans-dihydrokaempferol, (2R,3R)-(+)-dihydrokaempferol, (2R,3R)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one, (2R,3R)-dihydrokaempferol, (2R,3R)-trans-dihydrokaempferol, (2R/3R)-dihydrokaempferol, 2R,3R-trans-dihydrokaempferol, trans-dihydrokaempferol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2R/3R)-dihydrokaempferol + 2-oxoglutarate + O2 = kaempferol + succinate + CO2 + H2O
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(+)-dihydrokaempferol = maesopsin
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
naringenin + 2-oxoglutarate + O2 = apigenin + 2R,3R-trans-dihydrokaempferol + succinate + CO2 + 2 H2O
show the reaction diagram
-
-
(2S)-naringenin + 2-oxoglutarate + O2 = (2R,3S)-cis-dihydrokaempferol + (2R,3R)-trans-dihydrokaempferol + apigenin + kaempferol + succinate + CO2 + H2O
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition
-

Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.024
-
in 10 mM Tris/HCl buffer (pH 8.0), at 37°C

References & Links

Links to other databases for (+)-dihydrokaempferol

ChEBI
PubChem
ChEBI
PubChem