Ligand N6-L-threonylcarbamoyladenine37 in tRNA
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Basic Ligand Information
Molecular Structure

C43H55N16O33P4R
N6-L-threonylcarbamoyladenine37 in tRNA
Show all BRENDA pathways known for N6-L-threonylcarbamoyladenine37 in tRNA
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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N6-L-threonylcarbamoyladenine37 in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N6-L-threonylcarbamoyladenine37 in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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L-threonylcarbamoyladenylate + adenine37 in tRNA = AMP + N6-L-threonylcarbamoyladenine37 in tRNA
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Substrate in Enzyme-catalyzed Reactions (1 result)
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N6-L-threonylcarbamoyladenine37 in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N6-L-threonylcarbamoyladenine37 in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine
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Product in Enzyme-catalyzed Reactions (1 result)
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L-threonylcarbamoyladenylate + adenine37 in tRNA = AMP + N6-L-threonylcarbamoyladenine37 in tRNA
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA
2010
Arragain, S.; Handelman, S.K.; Forouhar, F.; Wei, F.Y.; Tomizawa, K.; Hunt, J.F.; Douki, T.; Fontecave, M.; Mulliez, E.; Atta, M.
J. Biol. Chem.
285
28425-28433
Links to other databases for N6-L-threonylcarbamoyladenine37 in tRNA