Ligand 2-methylfumaryl-CoA

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Basic Ligand Information

Molecular Structure
Picture of 2-methylfumaryl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C26H40N7O19P3S
2-methylfumaryl-CoA
LVBVWNJPMXCQJE-CBBDEUQJSA-N
Synonyms:
mesaconyl-C1-CoA, mesaconyl-CoA


Show all pahtways known for Show all BRENDA pathways known for 2-methylfumaryl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
2-methylfumaryl-CoA = 3-methylfumaryl-CoA
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
(2S)-methylsuccinyl-CoA + electron-transfer flavoprotein = 2-methylfumaryl-CoA + reduced electron-transfer flavoprotein
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-
show the reaction diagram
mesaconate + succinyl-CoA = 2-methylfumaryl-CoA + succinate
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-
show the reaction diagram
(2R,3S)-2-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
-
-
show the reaction diagram
beta-methylmalyl-CoA = mesaconyl-CoA + H2O
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
2-methylfumaryl-CoA = 3-methylfumaryl-CoA
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
(2S)-methylsuccinyl-CoA + electron-transfer flavoprotein = 2-methylfumaryl-CoA + reduced electron-transfer flavoprotein
-
-
show the reaction diagram
mesaconate + succinyl-CoA = 2-methylfumaryl-CoA + succinate
-
-
show the reaction diagram
(2R,3S)-2-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
-
-
show the reaction diagram
beta-methylmalyl-CoA = mesaconyl-CoA + H2O
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
55°C, pH not specified in the publication
840
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KM Value (1 result)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
37°C, pH 7.8
1
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References & Links

Links to other databases for 2-methylfumaryl-CoA

ChEBI
PubChem
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PubChem