We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Ligand protopanaxatriol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C3 0 H5 2 O4
protopanaxatriol
SHCBCKBYTHZQGZ-PHFGEWBZSA-N
a protopanaxatriol-type ginsenoside with no glycosidic modification at position 6
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
UDP-alpha-D-glucose + protopanaxatriol = UDP + ginsenoside Rh1
-
In Vivo Product in Enzyme-catalyzed Reactions (8 results)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
protopanaxadiol + [reduced NADPH-hemoprotein reductase] + O2 = protopanaxatriol + [oxidized NADPH-hemoprotein reductase] + H2O
-
ginsenoside F1 + H2O = protopanaxatriol + D-glucose
-
ginsenoside F1 + H2O = protopanaxatriol + D-glucose
-
ginsenoside Rf + H2O = protopanaxatriol + 2 D-glucose
-
ginsenoside Rg2 + 2 H2O = protopanaxatriol + D-glucose + L-rhamnose
-
ginsenoside Rg2 + H2O = protopanaxatriol + D-glucose + L-rhamnose
-
ginsenoside Rh1 + H2O = protopanaxatriol + D-glucose
-
ginsenoside Rg1 + H2O = protopanaxatriol + 2 D-glucose
-
Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
UDP-alpha-D-glucose + protopanaxatriol = UDP + ginsenoside Rh1
-
Product in Enzyme-catalyzed Reactions (8 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
protopanaxadiol + [reduced NADPH-hemoprotein reductase] + O2 = protopanaxatriol + [oxidized NADPH-hemoprotein reductase] + H2O
-
ginsenoside F1 + H2O = protopanaxatriol + D-glucose
-
ginsenoside F1 + H2O = protopanaxatriol + D-glucose
-
ginsenoside Rf + H2O = protopanaxatriol + 2 D-glucose
-
ginsenoside Rg2 + 2 H2O = protopanaxatriol + D-glucose + L-rhamnose
-
ginsenoside Rg2 + H2O = protopanaxatriol + D-glucose + L-rhamnose
-
ginsenoside Rh1 + H2O = protopanaxatriol + D-glucose
-
ginsenoside Rg1 + H2O = protopanaxatriol + 2 D-glucose
-
Inhibitor in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
noncompetitive inhibition
-
Enzyme Kinetic Parameters
IC50 Value (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
References & Links Literature References (3)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Determination of kinetic parameters and structure-activity relationships of ginsenosides as inhibitors of cyclin-dependent kinase 5/p25 using ultra-pressure liquid chromatography with triple quadrupole tandem mass spectrometry
2013
Chen, N.; Yang, H.; Niu, J.; Liu, S.
Rapid Commun. Mass Spectrom.
27
985-992
Advances in ginsenoside biosynthesis and metabolic regulation
2018
Lu, J.; Li, J.; Wang, S.; Yao, L.; Liang, W.; Wang, J.; Gao, W.
Biotechnol. Appl. Biochem.
65
514-522
Fungal elicitors enhance ginsenosides biosynthesis, expression of functional genes as well as signal molecules accumulation in adventitious roots of Panax ginseng C. A. Mey
2016
Li, J.; Liu, S.; Wang, J.; Li, J.; Liu, D.; Li, J.; Gao, W.
J. Biotechnol.
239
106-114
Links to other databases for protopanaxatriol
Show all BRENDA pathways known for protopanaxatriol
close all tables 
open all tables
top
