Ligand DL-homoserine lactone
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Basic Ligand Information
C4H7NO2
DL-homoserine lactone
QJPWUUJVYOJNMH-UHFFFAOYSA-N
2-aminobutan-4-olide, alpha-amino-gamma-butyrolactone
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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S-adenosyl-L-methionine = 5'-methylthioadenosine + alpha-amino-gamma-butyrolactone
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Product in Enzyme-catalyzed Reactions (7 results)
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N-decanoyl-DL-homoserine lactone + H2O = DL-homoserine lactone + decanoate
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N-dodecanoyl-DL-homoserine lactone + H2O = DL-homoserine lactone + dodecanoate
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N-heptanoyl-DL-homoserine lactone + H2O = DL-homoserine lactone + heptanoate
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N-octanoyl-DL-homoserine lactone + H2O = DL-homoserine lactone + octanoate
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N-tetradecanoyl-DL-homoserine lactone + H2O = DL-homoserine lactone + tetradecanoate
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S-adenosyl-L-methionine = 5'-methylthioadenosine + 2-aminobutan-4-olide
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S-adenosyl-L-methionine = 5'-methylthioadenosine + alpha-amino-gamma-butyrolactone
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Enzyme Kinetic Parameters
References & Links
Literature References (4)
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Enzymatic cleavage of S-adenosylmethionine
1959
Mudd, S.H.
J. Biol. Chem.
234
87-92
The mechanism of the enzymatic cleavage of S-adenosylmethionine to alpha-amino-gamma-butyrolactone
1959
Mudd, S.H.
J. Biol. Chem.
234
1784-1786
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T3 and UV-T3-induced S-adenosylmethionine cleavage enzyme (Escherichia coli)
1971
Gefter, M.L.
Methods Enzymol.
17 B
406-411
Nicotinamide methyltransferase and S-adenosylmethionine: 5-methylthioadenosine hydrolase. Control of transfer ribonucleic acid methylation
1973
Swiatek, K.R.; Simon, L.N.; Chao, K.L.
Biochemistry
12
4670-4674
Links to other databases for DL-homoserine lactone