Ligand [ubiquitin-activating protein Uba1a]-L-cysteine
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Basic Ligand Information
[ubiquitin-activating protein Uba1a]-L-cysteine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + ubiquitin + [ubiquitin-activating protein Uba1a]-L-cysteine = AMP + diphosphate + [ubiquitin-activating protein Uba1a]-S-ubiquitinyl-L-cysteine
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Product in Enzyme-catalyzed Reactions (1 result)
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[ubiquitin-activating protein Uba1a]-S-ubiquitinyl-L-cysteine + [ubiquitin-carrier-protein Ubc2b]-L-cysteine = [ubiquitin-activating protein Uba1a]-L-cysteine + [ubiquitin-carrier-protein Ubc2b]-S-ubiquitinyl-L-cysteine
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Pleiotropic effects of ATP*Mg2+ binding in the catalytic cycle of ubiquitin-activating enzyme
2006
Tokgoez, Z.; Bohnsack, R.N.; Haas, A.L.
J. Biol. Chem.
281
14729-14737
Links to other databases for [ubiquitin-activating protein Uba1a]-L-cysteine