Ligand 1,7-Diaminoheptane

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Basic Ligand Information

Molecular Structure
Picture of 1,7-Diaminoheptane (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H18N2
1,7-Diaminoheptane
PWSKHLMYTZNYKO-UHFFFAOYSA-N
Synonyms:
diaminoheptane

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,7-diaminoheptane + pyruvate = 1-aminoheptane + alanine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,7-diaminoheptane + O2 + H2O = ?
show the reaction diagram
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1,7-diaminoheptane + H2O + O2 = 7-aminoheptanal + NH3 + H2O2
show the reaction diagram
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1,7-diaminoheptane + acceptor + H2O = ?
show the reaction diagram
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caffeoyl-CoA + diaminoheptane = CoA + N-caffeoyl-1,7-diaminoheptane
show the reaction diagram
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acetyl-CoA + 1,7-diaminoheptane = CoA + N1-acetyl-1,7-diaminoheptane
show the reaction diagram
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putrescine + 1,7-diaminoheptane = homospermidine + N-(4-aminobutyl)-1,7-diaminoheptane
show the reaction diagram
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1,7-diaminoheptane + pyruvate = 1-aminoheptane + alanine
show the reaction diagram
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1,7-diaminoheptane + 2-oxoglutarate = 7-aminoheptanal + L-glutamate
show the reaction diagram
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1,7-diaminoheptane + pyruvate = ? + L-alanine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-carbamoyldiaminoheptane + H2O = CO2 + NH3 + diaminoheptane
show the reaction diagram
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1-amino-7-guanidinoheptane + H2O = 1,7-diaminoheptane + urea
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
45% of activation by putrescine
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Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
91% of initial activity at 2 mM
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weaker inhibitor
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22% inhibition at concentration of 5.0 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.59
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Ki Value (4 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0082
-
-
0.0004
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pH 6.0, 25°C
0.0009
-
-
0.0025
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References & Links

Links to other databases for 1,7-Diaminoheptane

ChEBI
PubChem
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PubChem