Ligand pentanal

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Basic Ligand Information

Molecular Structure
Picture of pentanal (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H10O
pentanal
WBAXJMCUFIXCNI-WDSKDSINSA-N
Synonyms:
1-Pentanal, 4-methylbutanal, n-Pentanal, n-pentylaldehyde, n-Valeraldehyde, pentaldehyde, pentanaldehyde, Valeraldehyde, valerylaldehyde

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-pentanol + NAD(P)+ = pentanal + NAD(P)H + H+
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n-pentanol + O2 = n-pentanal + H2O2
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pentanesulfonate + FMNH2 + O2 = pentanal + FMN + sulfite + H2O
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Substrate in Enzyme-catalyzed Reactions (86 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
valeraldehyde + NADH + H+ = pentan-1-ol + NAD+
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n-pentanal + NAD(P)H + H+ = n-pentanol + NAD(P)+
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pentanal + NADPH = pentanol + NADP+
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pentanal + NADPH + H+ = 1-pentanol + NAD(P)+
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n-pentanal + NADPH + H+ = n-pentanol + NADP+
show the reaction diagram
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pentanal + NADPH = pentanol + NADP+
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pentanal + acceptor + H2O = pentanoic acid + reduced acceptor
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valeraldehyde + phosphate + NAD+ = pentanoyl phosphate + NADH
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valeraldehyde + NAD+ + H2O = valerate + NADH + H+
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valeraldehyde + NAD+ + H2O = valeric acid + NADH + H+
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valeraldehyde + NAD(P)+ + H2O = n-pentanoate + NAD(P)H + H+
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pentanal + NAD+ = pentanoate + NADH
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valeraldehyde + coenzyme A + NADP+ = n-valeryl-CoA + NADPH + H+
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valeraldehyde + NADP+ + H2O = valerate + NADPH + H+
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n-pentanal + NADP+ + H2O = n-pentanoate + NADPH + H+
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pentaldehyde + CoA + NAD+ = pentanoyl-CoA + NADH + H+
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valeraldehyde + NAD+ + H2O = pentanoate + NADH + H+
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Pentanal + benzyl viologen = Pentanoate + reduced benzyl viologen
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pentanal + H2O + benzylviologen = pentanoate + reduced benzylviologen
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taurine + pentanal = 2-sulfoacetaldehyde + pentylamine
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phenylpyruvate + pentanal = 3-hydroxy-1-phenyl-2-heptanone
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n-pentanal = (R)-6-hydroxydecan-5-one
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HCN + pentanal = (R)-2-hydroxy-hexanenitrile
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2 pentanaldehyde = 5,6,7,8-tetradeoxy-D-threo-2-octulose
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D-ribulose 5-phosphate + valeraldehyde = ?
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pyruvate + pentaldehyde = ?
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pyruvate + pentaldehyde = ?
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pentanal + O2 + 2 NADH + 2 H+ = butane + formate + H2O + 2 NAD+
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pentanal + [(Z)-2-nitroethenyl]benzene = (2R)-2-[(1S)-2-nitro-1-phenylethyl]pentanal
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Product in Enzyme-catalyzed Reactions (80 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
n-pentanol + NAD+ + H2O = n-pentanal + NADH
show the reaction diagram
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1-pentanol + NAD+ = n-pentanal + NADH
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1-pentanol + NAD+ = pentanal + NADH + H+
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n-pentanol + NAD+ = n-pentanal + NADH
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n-pentanol + NADP+ = n-pentanal + NADPH
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1-pentanol + ferricytochrome c = pentanal + ferrocytochrome c + H+
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1-pentanol + O2 = n-pentanal + H2O2
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1-pentanol + a quinone = pentanal + a quinol
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1-pentanol + acceptor = n-pentanal + reduced acceptor
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pentanesulfonic acid + 2-oxoglutarate + O2 = sulfite + pentanal + succinate + CO2
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pentanesulfonate + FMNH2 + O2 = pentanal + FMN + sulfite + H2O
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pentanesulfonic acid + FMNH2 + O2 = pentaldehyde + FMN + sulfite + H2O
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pentane + duroquinol + O2 = 2-pentanol + pentanal + duroquinone + H2O
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1-pentanol + p-nitroso-N,N-dimethylaniline = n-pentanal + reduced p-nitroso-N,N-dimethylaniline
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trans-2-pentenal + NADPH = pentanal + NADP+
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n-pentylamine + H2O + O2 = pentaldehyde + NH3 + H2O2
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pentylamine + H2O + 2,6-dichlorophenol indophenol = pentanal + NH3 + reduced 2,6-dichlorophenol indophenol
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2-pentenal + NADPH = pentanal + NADP+
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1-nitropentane + O2 = pentanaldehyde + HNO2
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1-aminopentane + pyruvate = pentanal + L-alanine
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1-amylamine + pyruvate = pentanaldehyde + L-alanine
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Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
presence of NADPH, Ki: 3.9 mM, presence of NADH, Ki: 13.9 mM
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competitive inhibitor with respect to ethylnitronate as substrate
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substrate n-butanol
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extremely strong substrate inhibition
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substrate inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (29 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1
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pH 7.0, 37°C
13
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mutant enzyme I195A, at 25°C in 100 mM HEPES buffer (pH 8.0)
2.1
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5.16
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in 50 mM Tris-HCl (pH 7.5), at 25°C

KM Value (56 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.16
-
pH 7.0, 37°C
0.087
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0.145
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0.01
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0.3
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in 50 mM Tris-HCl (pH 7.5), at 25°C
0.061
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pH 8.2

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
58
-
pH 7.4, 30°C
1.9
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substrate n-butanol
0.33
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pH 8.2

References & Links

Links to other databases for pentanal

ChEBI
PubChem
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PubChem