Ligand phosphopantetheinylated EntB
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Basic Ligand Information
phosphopantetheinylated EntB
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + 2,3-dihydroxybenzoate + phosphopantetheinylated EntB = arylated EntB + AMP + diphosphate
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Substrate in Enzyme-catalyzed Reactions (4 results)
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ATP + 2,3-dihydroxybenzoate + phosphopantetheinylated EntB = arylated EntB + AMP + diphosphate
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ATP + 3-hydroxybenzoate + phosphopantetheinylated EntB = arylated EntB + AMP + diphosphate
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ATP + 4-aminosalicylic acid + phosphopantetheinylated EntB = arylated EntB + AMP + diphosphate
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ATP + salicylic acid + phosphopantetheinylated EntB = arylated EntB + AMP + diphosphate
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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2.8
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pH 7.8, 25°C, recombinant EntE
KM Value (1 result)
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0.0029
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pH 7.8, 25°C, recombinant EntE
References & Links
Literature References (1)
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Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli
2010
Sikora, A.L.; Wilson, D.J.; Aldrich, C.C.; Blanchard, J.S.
Biochemistry
49
3648-3657
Links to other databases for phosphopantetheinylated EntB