Ligand CDP-dimyristoylglycerol
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Basic Ligand Information
Molecular Structure

C40H73N3O15P2
CDP-dimyristoylglycerol
ICFWXMWHAMIZGF-WNAWUNHNSA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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CDP-dimyristoylglycerol + 1,2-dioleoylphosphatidylglycerol = 1-(1-myristoyl-2-myristoyl-sn-glycero-3-phospho)-3-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
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CDP-dimyristoylglycerol + egg yolk phosphatidylglycerol = cardiolipin + CMP
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Enzyme Kinetic Parameters
KM Value (1 result)
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0.0016
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pH 8.5, 37°C, at optimal concentration of phospholipid activators
References & Links
Literature References (2)
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Identification and characterization of human cardiolipin synthase
2006
Houtkooper, R.H.; Akbari, H.; van Lenthe, H.; Kulik, W.; Wanders, R.J.; Frentzen, M.; Vaz, F.M.
FEBS Lett.
580
3059-3064
Solubilization, purification, and characterization of cardiolipin synthase from rat liver mitochondria. Demonstration of its phospholipid requirement
1991
Schlame, M.; Hostetler, K.Y.
J. Biol. Chem.
266
22398-22403
Links to other databases for CDP-dimyristoylglycerol