Ligand (R)-mevaldehyde

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Basic Ligand Information

Molecular Structure
Picture of (R)-mevaldehyde (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H10O3
(R)-mevaldehyde
KJLUILOCNALPNM-RXMQYKEDSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
(R)-mevaldehyde + NADPH + H+ = (R)-mevalonate + NADP+
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Enzyme Kinetic Parameters

KM Value (4 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
pH 7.3, 37°C, second step of the reaction, mutant enzyme 404D/H398Q with Asp is added at position 404
0.084
-
pH 7.3, 37°C, second step of the reaction, mutant enzyme 404N with Asp is added at position 404
0.031
-
pH 7.3, 37°C, second step of the reaction, mutant enzyme H398Q
0.1
-
pH 7.3, 37°C, second step of the reaction, wild-type enzyme
0.032
-

References & Links

Links to other databases for (R)-mevaldehyde

ChEBI
PubChem
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PubChem