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Ligand dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 6 H2 4 N2 O1 5 P2
dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose
GTUIYEAZCHHLMA-BGLXAFIRSA-N
3,6-dideoxy-3-oxo-dTDP-D-glucose, dTDP-3-dehydro-6-deoxy-alpha-D-glucose, dTDP-3-dehydro-6-deoxy-D-glucopyranose
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
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dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3-dehydro-6-deoxy-alpha-D-glucose
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Substrate in Enzyme-catalyzed Reactions (2 results)
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dTDP-3-dehydro-6-deoxy-alpha-D-glucose + NADPH + H+ = dTDP-quinovose + NADP+
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dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate = dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
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Product in Enzyme-catalyzed Reactions (3 results)
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dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
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dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose
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dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3-dehydro-6-deoxy-alpha-D-glucose
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Enzyme Kinetic Parameters
References & Links Literature References (2)
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Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies
2007
Melançon, C.E. 3rd.; Hong, L.; White, J.A.; Liu, Y.N.; Liu, H.W.
Biochemistry
46
577-590
Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose
2011
Kubiak, R.L.; Holden, H.M.
Biochemistry
50
5905-5917
Links to other databases for dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose