Ligand UDP-N-acetylmuramate

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Basic Ligand Information

Molecular Structure
Picture of UDP-N-acetylmuramate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H31N3O19P2
UDP-N-acetylmuramate
NQBRVZNDBBMBLJ-MQTLHLSBSA-N
Synonyms:
UDP-MurNAc, UDP-N-acetyl-3-D-muramate, UDP-N-acetyl-alpha-D-muramate, UDP-N-acetylmuramic acid, UDP-N-alpha-D-acetylmuramate


Show all pahtways known for Show all BRENDA pathways known for UDP-N-acetylmuramate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-MurNAc + H2O = UMP + ?
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ATP + UDP-N-alpha-D-acetylmuramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate
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ATP + L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + UDP-MurNAc = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (50 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-MurNAc + undecaprenyl phosphate = UMP + MurNAc-diphosphoundecaprenol
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UDP-MurNAc + H2O = UMP + ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UTP + N-acetyl-alpha-D-muramate 1-phosphate = UDP-N-acetyl-alpha-D-muramate + diphosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
1 mM, relative enzyme activity 2%
-

3D Structure of Enzyme-Ligand-Complex (PDB) (36 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
4.83
-
pH 8.4, 37°C

KM Value (15 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.25
-
pH 8.4, 37°C

References & Links

Links to other databases for UDP-N-acetylmuramate

ChEBI
PubChem
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PubChem