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Ligand 3-sulfolactaldehyde

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for 3-sulfolactaldehyde

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.373

2-hydroxy-3-oxopropane-1-sulfonate + NADH + H+ = 2,3-dihydroxypropane-1-sulfonate + NAD+

762529

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1.1.1.373

3-sulfolactaldehyde + NADH + H+ = 2,3-dihydroxypropane-1-sulfonate + NAD+

730468

-

1.1.1.373

2 entries

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

4.1.2.57

6-deoxy-6-sulfo-D-fructose 1-phosphate = glycerone phosphate + 2-hydroxy-3-oxopropane-1-sulfonate

0

-

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.373

2-hydroxy-3-oxopropane-1-sulfonate + NADH + H+ = 2,3-dihydroxypropane-1-sulfonate + NAD+

762529

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1.1.1.373

3-sulfolactaldehyde + NADH + H+ = 2,3-dihydroxypropane-1-sulfonate + NAD+

730468

-

1.1.1.373

2 entries

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

4.1.2.57

6-deoxy-6-sulfo-D-fructose 1-phosphate = glycerone phosphate + 2-hydroxy-3-oxopropane-1-sulfonate

0

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (4 results)

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Show Turnover Number (4 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.1.1.373

27

-

enzyme mutant T124G, pH and temperature not specified in the publication

762529

1.1.1.373

68

-

enzyme mutant R123G, pH and temperature not specified in the publication

762529

1.1.1.373

71

-

enzyme mutant G122S, pH and temperature not specified in the publication

762529

1.1.1.373

332

-

wild-type enzyme, pH and temperature not specified in the publication

762529

1.1.1.373

4 entries

K_M Value (4 results)

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Show KM Value (4 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.1.1.373

0.3

-

wild-type enzyme, pH and temperature not specified in the publication

762529

1.1.1.373

1.63

-

enzyme mutant G122S, pH and temperature not specified in the publication

762529

1.1.1.373

5.74

-

enzyme mutant T124G, pH and temperature not specified in the publication

762529

1.1.1.373

7.99

-

enzyme mutant R123G, pH and temperature not specified in the publication

762529

1.1.1.373

4 entries

References & Links

Literature References (2)

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Show Reference (2 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

730468

24463506

Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle

2014

Denger, K.; Weiss, M.; Felux, A.; Schneider, A.; Mayer, C.; Spiteller, D.; Huhn, T.; Cook, A.; Schleheck, D.

Nature

507

114-117

762529

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Dynamic structural changes accompany the production of dihydroxypropanesulfonate by sulfolactaldehyde reductase

2020

Sharma, M.; Abayakoon, P.; Lingford, J.; Epa, R.; John, A.; Jin, Y.; Goddard-Borger, E.; Davies, G.; Williams, S.

ACS Catal.

10

2826-2836

Links to other databases for 3-sulfolactaldehyde

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Show Links (1 entry)

ChEBI

PubChem