Ligand 3-hydroxybiphenyl
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Basic Ligand Information
Molecular Structure

C12H10O
3-hydroxybiphenyl
UBXYXCRCOKCZIT-UHFFFAOYSA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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3-phenylphenol + NADH + H+ + O2 = (2R,3S)-2,3-dihydro[1,1'-biphenyl]-2,3,5-triol + (2S)-[1,1'-biphenyl]-2,3,3(2H)-triol + NAD+
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3-hydroxybiphenyl + FMNH2 + O2 = 2,3-dihydroxybiphenyl + FMN + H2O
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Product in Enzyme-catalyzed Reactions (2 results)
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biphenyl + NAD(P)H + H+ + O2 = 2-hydroxybiphenyl + 3-hydroxybiphenyl + biphenyl dihydrodiol + NAD(P)+
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biphenyl + NAD(P)H + H+ + O2 = cis-2,3-dihydroxy-2,3-dihydrobiphenyl + 2-hydroxybiphenyl + 3-hydroxybiphenyl + NAD(P)+
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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flavin: FMNH2, pH 7.4, 25°C
0.11
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KM Value (1 result)
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flavin: FMNH2, pH 7.4, 25°C
1.44
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References & Links
Literature References (2)
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A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism
2010
Dresen, C.; Lin, L.Y.; D'Angelo, I.; Tocheva, E.I.; Strynadka, N.; Eltis, L.D.
J. Biol. Chem.
285
22264-22275
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Oxidative biotransformations of phenol substrates catalysed by toluene dioxygenase A molecular docking study
2016
Hoering, P.; Rothschild-Mancinelli, K.; Sharma, N.; Boyd, D.; Allen, C.
J. Mol. Catal. B
134
396-406
Links to other databases for 3-hydroxybiphenyl