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BRENDA support

Ligand acrylic acid

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Basic Ligand Information

Molecular Structure
Picture of acrylic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H4O2
acrylic acid
NIXOWILDQLNWCW-UHFFFAOYSA-N
Synonyms:
Acrylate, prop-2-enoic acid, Propenoate, Propenoic acid


Show all pahtways known for Show all BRENDA pathways known for acrylic acid

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S,S-dimethyl-beta-propiothetin = dimethyl sulfide + acrylate
show the reaction diagram

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acrylic acid + NADH = propanoic acid + NAD+
show the reaction diagram
-
acrylic acid + methyl viologen = ?
show the reaction diagram
-
acetyl-CoA + acrylate = acrylyl-CoA + acetate
show the reaction diagram
-
acrylate + succinyl-CoA = ? + succinate
show the reaction diagram
-
acrylate + acetoacetyl-CoA = acrylyl-CoA + acetoacetate
show the reaction diagram
-
ATP + acrylate + CoA = AMP + diphosphate + acryloyl-CoA
show the reaction diagram
-
acrylate + ATP + coenzyme A = acryloyl-CoA + AMP + diphosphate
show the reaction diagram
-
ATP + acrylate + CoA = AMP + diphosphate + acryloyl-CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (26 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acrylaldehyde + NAD+ + H2O = acrylate + NADH
show the reaction diagram
-
acrolein + H2O + O2 = acrylic acid + H2O2
show the reaction diagram
-
acrylamide + H2O = acrylic acid + NH3
show the reaction diagram
-
acrylamide + H2O = acrylic acid + NH3
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
1.25 mM, catecholase activity: 342%
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
43% inhibition at 11 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (163 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (10 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
5.4
-
pH 8.5, 45°C

KM Value (15 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10
-
cosubstrate acetyl-CoA
39.3
-
37°C, pH 7.8
40
-
pH 7.5, 25°C
1.42
-
pH 8.5, 45°C

References & Links

Links to other databases for acrylic acid

ChEBI
PubChem
ChEBI
PubChem