Ligand 4-(2-hydroxyethyl)phenol

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Basic Ligand Information

Molecular Structure
Picture of 4-(2-hydroxyethyl)phenol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H10O2
4-(2-hydroxyethyl)phenol
YCCILVSKPBXVIP-UHFFFAOYSA-N
Synonyms:
2-(4'-hydroxyphenyl)ethanol, 4-hydroxyphenylethanol, 4-hydroxyphenylethyl alcohol, 4-hydroxyphenylethylalcohol, 4-tyrosol, p-hydroxyphenylethanol, p-tyrosol, tyrosol


Show all pahtways known for Show all BRENDA pathways known for 4-(2-hydroxyethyl)phenol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-(4'-Hydroxyphenyl)ethanol + O2 = ?
show the reaction diagram
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tyrosol + O2 = ?
show the reaction diagram
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p-tyrosol + 2 NADH + 2 H+ + O2 = 3,4-dihydroxyphenylethanol + 2 NAD+ + 2 H2O
show the reaction diagram
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tyrosol + NADH + H+ + O2 = hydroxytyrosol + NAD+ + H2O
show the reaction diagram
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4-hydroxyphenylethanol + O2 + NADH + H+ = 3,4-dihydroxyphenylethanol + H2O + NAD+
show the reaction diagram
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UDP-glucose + 4-hydroxyphenylethanol = UDP + 4-hydroxyphenylethyl beta-D-glucoside
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-hydroxyphenylacetaldehyde + NAD(P)H = 4-hydroxyphenylethyl alcohol + NAD(P)+
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
the compound is a substrate and an inhibitor for tyrosinase, 18% inhibition at 1.5 mM
compound from Rhodiola rosea extract, inhibits MAO B, not MAO A
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0.048 microM, results in 50% inhibition in interleukin 1beta effect on catalytic activity
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.004
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KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.1
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Ki Value (4 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 4-(2-hydroxyethyl)phenol

ChEBI
PubChem
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PubChem