print visible entries

print all entries

Ligand benzothiophene

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.14.21

benzothiophene + 2 FMNH2 + 2 O2 = benzothiophene-5,5-dioxide + 2 FMN + 2 H2O

736118

-

Substrate in Enzyme-catalyzed Reactions (3 results)

top print hide

Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.2.2

benzothiophene + H2O2 + H+ = ?

711125

-

1.14.14.11

benzo[b]thiophene + FADH2 + O2 = benzo[b]thiophene sulfoxide + FAD + H2O

726776

-

1.14.14.21

benzothiophene + 2 FMNH2 + 2 O2 = benzothiophene-5,5-dioxide + 2 FMN + 2 H2O

736118, 735526

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (2 results)

top print hide

Show Turnover Number (2 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.11.2.2

1

-

in the absence of NaCl, in 50 mM acetate buffer, pH 5.0, at 20°C

711125

1.11.2.2

1.6

-

in the presence of 100 mM NaCl, in 50 mM acetate buffer, pH 5.0, at 20°C

711125

1.11.2.2

2 entries

K_M Value (3 results)

top print hide

Show KM Value (3 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.11.2.2

0.072

-

in the presence of 100 mM NaCl, in 50 mM acetate buffer, pH 5.0, at 20°C

711125

1.11.2.2

0.081

-

in the absence of NaCl, in 50 mM acetate buffer, pH 5.0, at 20°C

711125

1.11.2.2

2 entries

1.14.14.21

0.36

-

pH 7.0, 55°C

735526

References & Links

Literature References (4)

top print hide

Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

711125

9742209

Sulphoxidation reaction catalysed by myeloperoxidase from human leucocytes

1998

Capeillere-Blandin, C.; Martin, C.; Gaggero, N.; Pasta, P.; Carrea, G.; Colonna, S.

Biochem. J.

335

27-33

726776

22890778

The oxidation of alkylaryl sulfides and benzo[b]thiophenes by Escherichia coli cells expressing wild-type and engineered styrene monooxygenase from Pseudomonas putida CA-3

2013

Nikodinovic-Runic, J.; Coulombel, L.; Francuski, D.; Sharma, N.D.; Boyd, D.R.; Ferrall, R.M.; O’Connor, K.E.

Appl. Microbiol. Biotechnol.

97

4849-4858

735526

12382053

Purification and characterization of the monooxygenase catalyzing sulfur-atom specific oxidation of dibenzothiophene and benzothiophene from the thermophilic bacterium Paenibacillus sp. strain A11-2

2003

Konishi, J.; Ishii, Y.; Onaka, T.; Maruhashi, K.

Appl. Microbiol. Biotechnol.

60

128-133

736118

10856644

Desulfurization of alkylated forms of both dibenzothiophene and benzothiophene by a single bacterial strain

2000

Kobayashi, M.; Onaka, T.; Ishii, Y.; Konishi, J.; Takaki, M.; Okada, H.; Ohta, Y.; Koizumi, K.; Suzuki, M.

FEMS Microbiol. Lett.

187

123-126

Links to other databases for benzothiophene

top print hide

Show Links (1 entry)

ChEBI

PubChem