Ligand 2-keto-L-gulonate

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Basic Ligand Information

Molecular Structure
Picture of 2-keto-L-gulonate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H10O7
2-keto-L-gulonate
VBUYCZFBVCCYFD-NUNKFHFFSA-N
Synonyms:
2-dehydro-L-gulonate, 2-dehydro-L-gulonic acid, 2-dehydro-L-idonate, 2-keto-L-gulonic acid, 2-keto-L-idonate, 2-oxo-L-gulonate, 2-oxo-L-gulonic acid, L-sorbosonic acid


Show all pahtways known for Show all BRENDA pathways known for 2-keto-L-gulonate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxo-L-gulonate + NADPH + H+ = L-idonate + NADP+
show the reaction diagram
-
2-dehydro-L-gulonic acid + NADPH + H+ = L-idonate + NADP+
show the reaction diagram
-
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,5-didehydro-D-gluconate + NADPH = 2-oxo-L-gulonic acid + NADP+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-L-gulonic acid + NADPH + H+ = L-idonate + NADP+
show the reaction diagram
-
2-keto-L-gulonate + NADH = 2,3-diketo-L-gulonate + NAD+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,5-didehydro-D-gluconate + NADPH + H+ = 2-dehydro-L-gulonate + NADP+
show the reaction diagram
-
-
L-sorbosone + acceptor = 2-keto-L-gulonate + reduced acceptor
show the reaction diagram
-

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
91
-
-
204
-
at pH 9.2 and 25C

References & Links

Links to other databases for 2-keto-L-gulonate

ChEBI
PubChem
ChEBI
PubChem