Ligand nitrosobenzene

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Basic Ligand Information

Molecular Structure
Picture of nitrosobenzene (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H5NO
nitrosobenzene
NLRKCXQQSUWLCH-UHFFFAOYSA-N
Synonyms:
4-nitrosobenzene

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
nitrosobenzene + NADPH + H+ = N-hydroxyaniline + NADP+ + H2O
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
aniline + cumene hydroperoxide = nitrosobenzene + ?
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
nitrosobenzene + NADPH + H+ = N-hydroxyaniline + NADP+ + H2O
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
aniline + cumene hydroperoxide = nitrosobenzene + ?
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
weak inhibitory activity
-
strong inhibition of isomerohydrolase activity in vitro at 0.2 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.208
-
at pH 8.0 and 37°C

References & Links

Links to other databases for nitrosobenzene

ChEBI
PubChem
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PubChem