Ligand Naphthalene

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of Naphthalene (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H8
Naphthalene
UFWIBTONFRDIAS-UHFFFAOYSA-N
Synonyms:
NPY

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
naphthalene + O2 = ?
-
show the reaction diagram
NPY + H2O = ?
-

Substrate in Enzyme-catalyzed Reactions (40 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
naphthalene + O2 = ?
-
show the reaction diagram
naphthalene + ? = ?
-
show the reaction diagram
naphthalene + O2 = ?
-
show the reaction diagram
naphthalene + NADH + H+ + O2 = 2-naphthol + NAD+ + H2O
-
show the reaction diagram
naphthalene + NADH + H+ + O2 = 1-naphthol + NAD+ + H2O
-
show the reaction diagram
naphthalene + FADH2 + O2 = (1R,2R)-1,2-dihydronaphthalene-1,2-diol + FAD + H2O
-
show the reaction diagram
NPY + H2O = ?
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
reversible
-

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (10 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
from Hill equation
3.6
-
from the dimer model
4.5
-
in potassium phosphate buffer, pH 7.0, at 25°C
166
-
in sodium phosphate-citrate buffer at pH 7.0 and 25°C
15
-
mutant enzyme F12Y/A14V/R15GA21D/V57A/L67F/V75I/I248V/F311L, at pH 7.0, temperature not specified in the publication
229
-
mutant enzyme G241D/R257K, at pH 7.0, temperature not specified in the publication
78
-
pH 5.5, 25°C
33
-
pH 5.6, 22°C
166
-
at 30°C in reaction mixtures containing 0.00013 mM ht-PhnI and 0.5 mM NADH in 50 mM potassium phosphate buffer, pH 7.0
1.82
-
pH 6.8, 30°C
2.4
-

KM Value (9 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
in potassium phosphate buffer, pH 7.0, at 25°C
0.32
-
in sodium phosphate-citrate buffer at pH 7.0 and 25°C
0.584
-
mutant enzyme F12Y/A14V/R15GA21D/V57A/L67F/V75I/I248V/F311L, at pH 7.0, temperature not specified in the publication
0.578
-
mutant enzyme G241D/R257K, at pH 7.0, temperature not specified in the publication
0.127
-
pH 5.5, 25°C
0.791
-
pH 5.6, 22°C
0.32
-
-
2.9
-
at 30°C in reaction mixtures containing 0.00013 mM ht-PhnI and 0.5 mM NADH in 50 mM potassium phosphate buffer, pH 7.0
0.00092
-
pH 6.8, 30°C
0.121
-

References & Links

Links to other databases for Naphthalene

ChEBI
PubChem
-
PubChem