Ligand view of aldehydo-D-mannose (182216 - GZCGUPFRVQAUEE-KVTDHHQDSA-N)

C₆H₁₂O₆

aldehydo-D-mannose

GZCGUPFRVQAUEE-KVTDHHQDSA-N

MetaCyc

2.7.1.191

[protein]-Npi-phospho-L-histidine + D-mannose[side 1] = [protein]-L-histidine + D-mannose 6-phosphate[side 2]

641881, 735528, 735736, 736038, 736124, 736390, 736822, 736835, 737176, 736762, 725288, 736382, 735488, 735479, 735566, 736355, 736759, 737297, 736117

-

2.7.1.191

[protein]-Npi-phospho-L-histidine + D-mannose[side 1] = [protein]-L-histidine + D-mannose 6-phosphate[side 2]

641881, 735528, 735736, 736038, 736124, 736390, 736822, 736835, 737176, 736762, 725288, 736382, 735488, 735479, 735566, 736355, 736759, 737297, 736117

-

2.7.1.199

[protein]-Npi-phospho-L-histidine + D-mannose[side 1] = [protein]-L-histidine + D-mannose 6-phosphate[side 2]

-

0.045

-

at pH 7.5 and 25Â°C

736382

2.7.1.199

0.04

-

at pH 7.5, temperature not specified in the publication

736382

641881

12657050

Soluble sugar permeases of the phosphotransferase system in Escherichia coli: Evidence for two physically distinct forms of the proteins in vivo

2003

Aboulwafa, M.; Saier, M.H., Jr.

Mol. Microbiol.

48

131-141

725288

23836865

Salmonella utilizes D-glucosaminate via a mannose family phosphotransferase system permease and associated enzymes

2013

Miller, K.A.; Phillips, R.S.; Mrazek, J.; Hoover, T.R.

J. Bacteriol.

195

4057-4066

735479

19734332

Regulation of mannose phosphotransferase system permease and virulence gene expression in Listeria monocytogenes by the EII(t)Man transporter

2009

Vu-Khac, H.; Miller, K.W.

Appl. Environ. Microbiol.

75

6671-6678

735488

23524676

Distribution and functions of phosphotransferase system genes in the genome of the lactic acid bacterium Oenococcus oeni

2013

Jamal, Z.; Miot-Sertier, C.; Thibau, F.; Dutilh, L.; Lonvaud-Funel, A.; Ballestra, P.; Le Marrec, C.; Dols-Lafargue, M.

Appl. Environ. Microbiol.

79

3371-3379

735528

17053901

Increase of organic solvent tolerance by overexpression of manXYZ in Escherichia coli

2007

Okochi, M.; Kurimoto, M.; Shimizu, K.; Honda, H.

Appl. Microbiol. Biotechnol.

73

1394-1399

735566

1953293

Release of glucose-mediated catabolite repression due to a defect in the membrane fraction of phosphoenolpyruvate: mannose phosphotransferase system in Pediococcus halophilus

1991

Abe, K.; Uchida, K.

Arch. Microbiol.

155

517-520

735736

7811395

The mannose transporter of Escherichia coli K12: oligomeric structure, and function of two conserved cysteines

1994

Rhiel, E.; Flukiger, K.; Wehrli, C.; Erni, B.

Biol. Chem. Hoppe-Seyler

375

551-560

736038

8774730

Membrane topology of the mannose transporter of Escherichia coli K12

1996

Huber, F.; Erni, B.

Eur. J. Biochem.

239

810-817

736117

8039653

Nucleotide sequence of the gene encoding the Corynebacterium glutamicum mannose enzyme II and analyses of the deduced protein sequence

1994

Lee, J.K.; Sung, M.H.; Yoon, K.H.; Yu, J.H.; Oh, T.K.

FEMS Microbiol. Lett.

119

137-145

736124

-

The ptsL, pel/ptsM (manXYZ) locus consists of three genes involved in mannose uptake in Escherichia coli K12

1987

Saris, P.; Palva, E.

FEMS Microbiol. Lett.

44

371-376

736355

20139185

Characterization of a mannose utilization system in Bacillus subtilis

2010

Sun, T.; Altenbuchner, J.

J. Bacteriol.

192

2128-2139

736382

6292227

Sugar transport by the bacterial phosphotransferase system. The glucose receptors of the Salmonella typhimurium phosphotransferase system

1982

Stock, J.; Waygood, E.; Meadow, N.; Postma, P.; Roseman, S.

J. Biol. Chem.

257

14543-14552

736390

8262947

The mannose transporter of Escherichia coli: Structure and function of the IIABMan subunit

1993

Stolz, B.; Huber, M.; Markovic-Housley, Z.; Erni, B.

J. Biol. Chem.

268

27094-27099

736759

10746771

The gene encoding IIABLMan in Streptococcus salivarius is part of a tetracistronic operon encoding a phosphoenolpyruvate: Mannose/glucose phosphotransferase system

2000

Lortie, L.; Pelletier, M.; Vadeboncoeur, C.; Frenette, M.

Microbiology

146

677-685

736762

11238974

Contribution of the phosphoenolpyruvate: Mannose phosphotransferase system to carbon catabolite repression in Lactobacillus pentosus

2001

Chaillou, S.; Postma, P.; Pouwels, P.

Microbiology

147

671-679

736822

9484892

Control of the expression of the manXYZ operon in Escherichia coli: Mlc is a negative regulator of the mannose PTS

1998

Plumbridge, J.

Mol. Microbiol.

27

369-380

736835

26411266

Diverse mechanisms of post-transcriptional repression by the small RNA regulator of glucose-phosphate stress

2016

Bobrovskyy, M.; Vanderpool, C.K.

Mol. Microbiol.

99

254-273

737176

2947241

Pel, the protein that permits lambda DNA penetration of Escherichia coli, is encoded by a gene in ptsM and is required for mannose utilization by the phosphotransferase system

1986

Williams, N.; Fox, D.; Shea, C.; Roseman, S.

Proc. Natl. Acad. Sci. USA

83

8934-8938

737297

15708813

Putative mannose-specific phosphotransferase system component IID represses expression of suilysin in serotype 2 Streptococcus suis

2005

Lun, S.; Willson, P.J.

Vet. Microbiol.

105

169-180

Ligand aldehydo-D-mannose

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

Substrate in Enzyme-catalyzed Reactions (2 results)

3D Structure of Enzyme-Ligand-Complex (PDB) (7 results)

Enzyme Kinetic Parameters

K_M Value (2 results)

References & Links

Literature References (19)

Links to other databases for aldehydo-D-mannose

Ligand aldehydo-D-mannose

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

Substrate in Enzyme-catalyzed Reactions (2 results)

3D Structure of Enzyme-Ligand-Complex (PDB) (7 results)

Enzyme Kinetic Parameters

KM Value (2 results)

References & Links

Literature References (19)

Links to other databases for aldehydo-D-mannose

K_M Value (2 results)