Ligand 2-cis,6-trans-farnesyl diphosphate

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Basic Ligand Information

Molecular Structure
Picture of 2-cis,6-trans-farnesyl diphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H28O7P2
2-cis,6-trans-farnesyl diphosphate
VWFJDQUYCIWHTN-PVMFERMNSA-N
Synonyms:
(2Z,6E)-farnesyl diphosphate, (2Z, 6E)-farnesyl diphosphate, (Z,E)-farnesyl diphosphate, 2,3-cis,6,7-trans-farnesyl diphosphate, trans,polycis-polyprenyl diphosphate (n = 9-11), Z,E-farnesyl diphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2Z, 6E)-farnesyl diphosphate = (-)-gamma-cadinene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = patchoulol + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (-)-beta-curcumene + diphosphate
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2Z,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate + trans,poly-cis-polyprenyl diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = beta-cubebene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (+)-sativene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate
show the reaction diagram
-
(Z,E)-farnesyl diphosphate = ?
show the reaction diagram
-
(2Z, 6E)-farnesyl diphosphate = (-)-gamma-cadinene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = patchoulol + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (+)-2-epiprezizaene + (-)-alpha-cedrene + (-)-beta-curcumene + alpha-acoradiene + 4-epi-alpha-acoradiene + alpha-bisabolol + epi-alpha-bisabolol + nerolidol + (2Z,6E)-farnesol + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate
show the reaction diagram
-
(2Z,6E)-farnesyl diphosphate = (-)-beta-curcumene + diphosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (12 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
11.5
-
pH 7.9, 37°C
0.072
-
at pH 7.3 and 38°C
0.095
-
in 200 mM Tris-HCl (pH 7.5), 40 mM MgCl2, at 22°C

KM Value (15 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.29
-
pH 7.9, 37°C
0.000036
-
pH 7.5
0.008
-
at pH 7.3 and 38°C
0.0143
-
in 200 mM Tris-HCl (pH 7.5), 40 mM MgCl2, at 22°C

References & Links

Links to other databases for 2-cis,6-trans-farnesyl diphosphate

ChEBI
PubChem
ChEBI
PubChem